FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071304873> ?p ?o ?g. }

• W2071304873 endingPage "216" @default.
• W2071304873 startingPage "211" @default.
• W2071304873 abstract "Escherichia coli asparaginase II catalyzes the hydrolysis of L-asparagine to L-aspartate via a threonine-bound acyl-enzyme intermediate. A nearly inactive mutant in which one of the active site threonines, Thr-89, was replaced by valine was constructed, expressed, and crystallized. Its structure, solved at 2.2 A resolution, shows high overall similarity to the wild-type enzyme, but an aspartyl moiety is covalently bound to Thr-12, resembling a reaction intermediate. Kinetic analysis confirms the deacylation deficiency, which is also explained on a structural basis. The previously identified oxyanion hole is described in more detail." @default.
• W2071304873 created "2016-06-24" @default.
• W2071304873 creator A5025797603 @default.
• W2071304873 creator A5027980832 @default.
• W2071304873 creator A5053769483 @default.
• W2071304873 creator A5067113624 @default.
• W2071304873 creator A5079702745 @default.
• W2071304873 creator A5085454160 @default.
• W2071304873 date "1996-07-22" @default.
• W2071304873 modified "2023-10-18" @default.
• W2071304873 title "A covalently bound catalytic intermediate in <i>Escherichia coli</i> asparaginase : Crystal structure of a Thr‐89‐Val mutant" @default.
• W2071304873 cites W1532676874 @default.
• W2071304873 cites W1553128399 @default.
• W2071304873 cites W1556674651 @default.
• W2071304873 cites W1580684552 @default.
• W2071304873 cites W1659928442 @default.
• W2071304873 cites W1901470441 @default.
• W2071304873 cites W1963961765 @default.
• W2071304873 cites W1966981228 @default.
• W2071304873 cites W1980876171 @default.
• W2071304873 cites W1985299228 @default.
• W2071304873 cites W1986397685 @default.
• W2071304873 cites W2002876578 @default.
• W2071304873 cites W2009682605 @default.
• W2071304873 cites W2011332592 @default.
• W2071304873 cites W2028334705 @default.
• W2071304873 cites W2037592320 @default.
• W2071304873 cites W2060448324 @default.
• W2071304873 cites W2062668527 @default.
• W2071304873 cites W2088749908 @default.
• W2071304873 cites W2112669896 @default.
• W2071304873 cites W2116275717 @default.
• W2071304873 cites W2117514600 @default.
• W2071304873 cites W2134482660 @default.
• W2071304873 doi "https://doi.org/10.1016/0014-5793(96)00660-6" @default.
• W2071304873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8706862" @default.
• W2071304873 hasPublicationYear "1996" @default.
• W2071304873 type Work @default.
• W2071304873 sameAs 2071304873 @default.
• W2071304873 citedByCount "88" @default.
• W2071304873 countsByYear W20713048732012 @default.
• W2071304873 countsByYear W20713048732013 @default.
• W2071304873 countsByYear W20713048732014 @default.
• W2071304873 countsByYear W20713048732015 @default.
• W2071304873 countsByYear W20713048732016 @default.
• W2071304873 countsByYear W20713048732017 @default.
• W2071304873 countsByYear W20713048732018 @default.
• W2071304873 countsByYear W20713048732019 @default.
• W2071304873 countsByYear W20713048732020 @default.
• W2071304873 countsByYear W20713048732021 @default.
• W2071304873 countsByYear W20713048732022 @default.
• W2071304873 countsByYear W20713048732023 @default.
• W2071304873 crossrefType "journal-article" @default.
• W2071304873 hasAuthorship W2071304873A5025797603 @default.
• W2071304873 hasAuthorship W2071304873A5027980832 @default.
• W2071304873 hasAuthorship W2071304873A5053769483 @default.
• W2071304873 hasAuthorship W2071304873A5067113624 @default.
• W2071304873 hasAuthorship W2071304873A5079702745 @default.
• W2071304873 hasAuthorship W2071304873A5085454160 @default.
• W2071304873 hasBestOaLocation W20713048731 @default.
• W2071304873 hasConcept C104317684 @default.
• W2071304873 hasConcept C143065580 @default.
• W2071304873 hasConcept C178790620 @default.
• W2071304873 hasConcept C179506582 @default.
• W2071304873 hasConcept C180577832 @default.
• W2071304873 hasConcept C181199279 @default.
• W2071304873 hasConcept C185592680 @default.
• W2071304873 hasConcept C2775880066 @default.
• W2071304873 hasConcept C2775895851 @default.
• W2071304873 hasConcept C2776414213 @default.
• W2071304873 hasConcept C2776568683 @default.
• W2071304873 hasConcept C2778461978 @default.
• W2071304873 hasConcept C2778904437 @default.
• W2071304873 hasConcept C2909962599 @default.
• W2071304873 hasConcept C41183919 @default.
• W2071304873 hasConcept C54355233 @default.
• W2071304873 hasConcept C547475151 @default.
• W2071304873 hasConcept C55493867 @default.
• W2071304873 hasConcept C71240020 @default.
• W2071304873 hasConcept C86803240 @default.
• W2071304873 hasConceptScore W2071304873C104317684 @default.
• W2071304873 hasConceptScore W2071304873C143065580 @default.
• W2071304873 hasConceptScore W2071304873C178790620 @default.
• W2071304873 hasConceptScore W2071304873C179506582 @default.
• W2071304873 hasConceptScore W2071304873C180577832 @default.
• W2071304873 hasConceptScore W2071304873C181199279 @default.
• W2071304873 hasConceptScore W2071304873C185592680 @default.
• W2071304873 hasConceptScore W2071304873C2775880066 @default.
• W2071304873 hasConceptScore W2071304873C2775895851 @default.
• W2071304873 hasConceptScore W2071304873C2776414213 @default.
• W2071304873 hasConceptScore W2071304873C2776568683 @default.
• W2071304873 hasConceptScore W2071304873C2778461978 @default.
• W2071304873 hasConceptScore W2071304873C2778904437 @default.
• W2071304873 hasConceptScore W2071304873C2909962599 @default.
• W2071304873 hasConceptScore W2071304873C41183919 @default.
• W2071304873 hasConceptScore W2071304873C54355233 @default.
• W2071304873 hasConceptScore W2071304873C547475151 @default.
• W2071304873 hasConceptScore W2071304873C55493867 @default.

• next