FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071359369> ?p ?o ?g. }

• W2071359369 endingPage "340" @default.
• W2071359369 startingPage "327" @default.
• W2071359369 abstract "Myogenesis is regulated by the MyoD class of myogenic regulatory factors (MRFs). These basic helix-loop-helix transcription factors dimerize with E proteins to bind conserved E-box sequences in the promoter regions of muscle-specific genes. Perhaps due to their expression in a wide array of tissues, the specific interactions of E proteins with different MRFs have been largely ignored. Likewise, the expression of E proteins in muscle tissue remains mostly uncharacterized. We investigated the expression of the E proteins HEB, E12, and E47 in rat L6 myoblasts, which express only embryonic and fast (2X) myosin heavy chains (MyHCs) in vitro, C2C12 myosatellite cells, and a number of muscle tissues, to determine whether myosin heavy chain diversity is mirrored by diversity in E protein or MRF expression. Although L6 and C2C12 myotubes demonstrate strong expression of embryonic and 2X (fast) MyHCs, immunofluorescence demonstrated the additional expression of type 1 (slow), 2A, and 2B MyHCs in the C2C12 cell line. Immunofluorescence and western blot analyses show that HEB was expressed in differentiating L6 myoblasts, C2C12 cells, and neonatal rat primary myotubes. In contrast, E12 and E47 expression was not detected in either cell line or in any adult muscle tissue examined. These data strongly implicate HEB in the development of skeletal muscle. However, because HEB is expressed in L6 myoblasts, C2C12 myosatellite cells, and neonatal hindlimb muscles, it is unlikely to be involved in a fiber type-specific manner, and may have a more general role in differentiation of myotubes." @default.
• W2071359369 created "2016-06-24" @default.
• W2071359369 creator A5007433062 @default.
• W2071359369 creator A5009578649 @default.
• W2071359369 creator A5047850802 @default.
• W2071359369 creator A5047964091 @default.
• W2071359369 date "2004-09-01" @default.
• W2071359369 modified "2023-09-25" @default.
• W2071359369 title "The E protein HEB is preferentially expressed in developing muscle" @default.
• W2071359369 cites W1526135982 @default.
• W2071359369 cites W1544492955 @default.
• W2071359369 cites W1835572484 @default.
• W2071359369 cites W1837450065 @default.
• W2071359369 cites W1928848452 @default.
• W2071359369 cites W1952579501 @default.
• W2071359369 cites W1954617482 @default.
• W2071359369 cites W1968897633 @default.
• W2071359369 cites W1968986466 @default.
• W2071359369 cites W1970823660 @default.
• W2071359369 cites W1972319143 @default.
• W2071359369 cites W1977341238 @default.
• W2071359369 cites W1994695193 @default.
• W2071359369 cites W1996626295 @default.
• W2071359369 cites W1996977570 @default.
• W2071359369 cites W1999737346 @default.
• W2071359369 cites W2018604626 @default.
• W2071359369 cites W2027987308 @default.
• W2071359369 cites W2030808245 @default.
• W2071359369 cites W2041401980 @default.
• W2071359369 cites W2047449018 @default.
• W2071359369 cites W2060569257 @default.
• W2071359369 cites W2061837851 @default.
• W2071359369 cites W2062064489 @default.
• W2071359369 cites W2067594063 @default.
• W2071359369 cites W2067945340 @default.
• W2071359369 cites W2068438291 @default.
• W2071359369 cites W2073096765 @default.
• W2071359369 cites W2078709292 @default.
• W2071359369 cites W2081797009 @default.
• W2071359369 cites W2081860139 @default.
• W2071359369 cites W2083405476 @default.
• W2071359369 cites W2085222009 @default.
• W2071359369 cites W2089337850 @default.
• W2071359369 cites W2100356921 @default.
• W2071359369 cites W2109769177 @default.
• W2071359369 cites W2113731866 @default.
• W2071359369 cites W2116242175 @default.
• W2071359369 cites W2118533478 @default.
• W2071359369 cites W2119483052 @default.
• W2071359369 cites W2119528854 @default.
• W2071359369 cites W2123499039 @default.
• W2071359369 cites W2138321124 @default.
• W2071359369 cites W2158499654 @default.
• W2071359369 cites W2163584800 @default.
• W2071359369 cites W286641498 @default.
• W2071359369 cites W4237140320 @default.
• W2071359369 cites W4238191426 @default.
• W2071359369 doi "https://doi.org/10.1111/j.1432-0436.2004.07207004.x" @default.
• W2071359369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15554944" @default.
• W2071359369 hasPublicationYear "2004" @default.
• W2071359369 type Work @default.
• W2071359369 sameAs 2071359369 @default.
• W2071359369 citedByCount "29" @default.
• W2071359369 countsByYear W20713593692012 @default.
• W2071359369 countsByYear W20713593692014 @default.
• W2071359369 countsByYear W20713593692016 @default.
• W2071359369 countsByYear W20713593692017 @default.
• W2071359369 countsByYear W20713593692018 @default.
• W2071359369 countsByYear W20713593692019 @default.
• W2071359369 countsByYear W20713593692020 @default.
• W2071359369 countsByYear W20713593692021 @default.
• W2071359369 countsByYear W20713593692022 @default.
• W2071359369 countsByYear W20713593692023 @default.
• W2071359369 crossrefType "journal-article" @default.
• W2071359369 hasAuthorship W2071359369A5007433062 @default.
• W2071359369 hasAuthorship W2071359369A5009578649 @default.
• W2071359369 hasAuthorship W2071359369A5047850802 @default.
• W2071359369 hasAuthorship W2071359369A5047964091 @default.
• W2071359369 hasConcept C105702510 @default.
• W2071359369 hasConcept C153911025 @default.
• W2071359369 hasConcept C207200792 @default.
• W2071359369 hasConcept C2778106681 @default.
• W2071359369 hasConcept C2779959927 @default.
• W2071359369 hasConcept C3763915 @default.
• W2071359369 hasConcept C60278653 @default.
• W2071359369 hasConcept C6997183 @default.
• W2071359369 hasConcept C86803240 @default.
• W2071359369 hasConcept C95444343 @default.
• W2071359369 hasConceptScore W2071359369C105702510 @default.
• W2071359369 hasConceptScore W2071359369C153911025 @default.
• W2071359369 hasConceptScore W2071359369C207200792 @default.
• W2071359369 hasConceptScore W2071359369C2778106681 @default.
• W2071359369 hasConceptScore W2071359369C2779959927 @default.
• W2071359369 hasConceptScore W2071359369C3763915 @default.
• W2071359369 hasConceptScore W2071359369C60278653 @default.
• W2071359369 hasConceptScore W2071359369C6997183 @default.
• W2071359369 hasConceptScore W2071359369C86803240 @default.
• W2071359369 hasConceptScore W2071359369C95444343 @default.

• next