FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071360917> ?p ?o ?g. }

• W2071360917 endingPage "52" @default.
• W2071360917 startingPage "48" @default.
• W2071360917 abstract "Background: Behcet's disease (BD) is an inflammatory disorder of unknown cause, associated with vasculitis. Arterial or venous thrombosis occurs in about 25% of BD patients. Familial Mediterranean fever (FMF) is another inflammatory disorder, which stems from mutations in the FMF gene (MEFV) and shares a number of features with BD.Objective: MEFV analysis in patients with BD suggests that mutated MEFV may act as a susceptibility gene in BD. We studied the rate and the clinical correlates of MEFV mutations in Israeli BD patients.Methods: Included were 54 BD patients who satisfied the International Study Group criteria for BD. All BD patients were genotyped using polymerase chain reaction (PCR) and restriction enzyme analysis for the three most common MEFV mutations (M694V, V726A, and E148Q). The association between BD manifestations and MEFV alleles was analysed.Results: Twenty‐one BD patients were found to carry a single MEFV mutation and three additional patients were compound heterozygotes, a frequency significantly higher than that expected for ethnically matched healthy individuals. There were no statistically significant differences between carriers and non‐carriers with respect to gender, frequency of HLA B5 antigen, cutaneous lesions, joint disease, and severity score. However, carriers did experience thrombosis more often [54% vs. 17%, p<0.005, odds ratio (OR) = 6.9, 95% confidence interval (CI) 1.75–26.9] and uveitis less often (20% vs. 40%, p<0.05, OR = 0.2, 95% CI 0.04–0.92).Conclusions: MEFV appears to be a susceptibility and modifier gene in BD." @default.
• W2071360917 created "2016-06-24" @default.
• W2071360917 creator A5004321069 @default.
• W2071360917 creator A5006884737 @default.
• W2071360917 creator A5025700190 @default.
• W2071360917 creator A5039822320 @default.
• W2071360917 creator A5073594118 @default.
• W2071360917 creator A5086731063 @default.
• W2071360917 date "2007-01-01" @default.
• W2071360917 modified "2023-09-25" @default.
• W2071360917 title "Common FMF alleles may predispose to development of Behcet's disease with increased risk for venous thrombosis" @default.
• W2071360917 cites W1964150904 @default.
• W2071360917 cites W1969019918 @default.
• W2071360917 cites W1969945757 @default.
• W2071360917 cites W1979658394 @default.
• W2071360917 cites W1992487962 @default.
• W2071360917 cites W1999280038 @default.
• W2071360917 cites W2003753226 @default.
• W2071360917 cites W2004684128 @default.
• W2071360917 cites W2006902197 @default.
• W2071360917 cites W2018398196 @default.
• W2071360917 cites W2042064495 @default.
• W2071360917 cites W2043528743 @default.
• W2071360917 cites W2045648170 @default.
• W2071360917 cites W2050549183 @default.
• W2071360917 cites W2059452521 @default.
• W2071360917 cites W2082066166 @default.
• W2071360917 cites W2087427136 @default.
• W2071360917 cites W2089678461 @default.
• W2071360917 cites W2095070094 @default.
• W2071360917 cites W2095834327 @default.
• W2071360917 cites W2110105853 @default.
• W2071360917 cites W2112413460 @default.
• W2071360917 cites W2113779816 @default.
• W2071360917 cites W2136219369 @default.
• W2071360917 cites W2140276493 @default.
• W2071360917 cites W2141752671 @default.
• W2071360917 cites W2151080688 @default.
• W2071360917 cites W2155253341 @default.
• W2071360917 cites W2169375209 @default.
• W2071360917 cites W2615194403 @default.
• W2071360917 cites W4235673640 @default.
• W2071360917 doi "https://doi.org/10.1080/03009740600759639" @default.
• W2071360917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17454935" @default.
• W2071360917 hasPublicationYear "2007" @default.
• W2071360917 type Work @default.
• W2071360917 sameAs 2071360917 @default.
• W2071360917 citedByCount "81" @default.
• W2071360917 countsByYear W20713609172012 @default.
• W2071360917 countsByYear W20713609172013 @default.
• W2071360917 countsByYear W20713609172014 @default.
• W2071360917 countsByYear W20713609172015 @default.
• W2071360917 countsByYear W20713609172016 @default.
• W2071360917 countsByYear W20713609172017 @default.
• W2071360917 countsByYear W20713609172019 @default.
• W2071360917 countsByYear W20713609172020 @default.
• W2071360917 countsByYear W20713609172021 @default.
• W2071360917 countsByYear W20713609172023 @default.
• W2071360917 crossrefType "journal-article" @default.
• W2071360917 hasAuthorship W2071360917A5004321069 @default.
• W2071360917 hasAuthorship W2071360917A5006884737 @default.
• W2071360917 hasAuthorship W2071360917A5025700190 @default.
• W2071360917 hasAuthorship W2071360917A5039822320 @default.
• W2071360917 hasAuthorship W2071360917A5073594118 @default.
• W2071360917 hasAuthorship W2071360917A5086731063 @default.
• W2071360917 hasConcept C104317684 @default.
• W2071360917 hasConcept C126322002 @default.
• W2071360917 hasConcept C156957248 @default.
• W2071360917 hasConcept C180754005 @default.
• W2071360917 hasConcept C203014093 @default.
• W2071360917 hasConcept C2779134260 @default.
• W2071360917 hasConcept C2779537928 @default.
• W2071360917 hasConcept C2780011451 @default.
• W2071360917 hasConcept C2780868729 @default.
• W2071360917 hasConcept C2781145326 @default.
• W2071360917 hasConcept C2781428731 @default.
• W2071360917 hasConcept C2994225774 @default.
• W2071360917 hasConcept C501734568 @default.
• W2071360917 hasConcept C54355233 @default.
• W2071360917 hasConcept C71924100 @default.
• W2071360917 hasConcept C86803240 @default.
• W2071360917 hasConcept C90924648 @default.
• W2071360917 hasConceptScore W2071360917C104317684 @default.
• W2071360917 hasConceptScore W2071360917C126322002 @default.
• W2071360917 hasConceptScore W2071360917C156957248 @default.
• W2071360917 hasConceptScore W2071360917C180754005 @default.
• W2071360917 hasConceptScore W2071360917C203014093 @default.
• W2071360917 hasConceptScore W2071360917C2779134260 @default.
• W2071360917 hasConceptScore W2071360917C2779537928 @default.
• W2071360917 hasConceptScore W2071360917C2780011451 @default.
• W2071360917 hasConceptScore W2071360917C2780868729 @default.
• W2071360917 hasConceptScore W2071360917C2781145326 @default.
• W2071360917 hasConceptScore W2071360917C2781428731 @default.
• W2071360917 hasConceptScore W2071360917C2994225774 @default.
• W2071360917 hasConceptScore W2071360917C501734568 @default.
• W2071360917 hasConceptScore W2071360917C54355233 @default.
• W2071360917 hasConceptScore W2071360917C71924100 @default.
• W2071360917 hasConceptScore W2071360917C86803240 @default.

• next