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- W2071363583 abstract "1 The effects of clonidine, UK-14,304, noradrenaline, para-aminoclonidine and phenylephrine were examined on the acid secretory response of the rat isolated gastric mucosa preparation to electrical field stimulation. 2 Clonidine, UK-14,304, noradrenaline and para-aminoclonidine but not phenylephrine (10 μM) reduced the response of the gastric mucosa stimulated at 2.5 Hz; gastric mucosae stimulated at higher frequencies were insensitive to the action of these α2-adrenoceptor agonists. 3 The inhibitory effect of the selective α2-adrenoceptor agonist UK-14,304 was antagonized by idazoxan but not by prazosin. 4 These findings indicate that clonidine and other α2-adrenoceptor agents inhibit the acid secretory response of the rat gastric mucosa to electrical field stimulation by an action at α2-adrenoceptors, which are probably located on cholinergic nerve terminals." @default.
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- W2071363583 date "1986-10-01" @default.
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- W2071363583 title "The effect of α2-adrenoceptor agonists on the acid secretory responses of rat isolated gastric mucosa to electrical field stimulation" @default.
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- W2071363583 doi "https://doi.org/10.1111/j.1476-5381.1986.tb10268.x" @default.
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