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• W2071427504 abstract "Rat E15 retina was grafted to the retina of adult rat hosts. After varying survival times (1 week–6 months), grafts were stained by immunohistochemistry for neurofilament 160 kDa (NF), HPC-1 (an amacrine cell marker), choline acetyltransferase (ChAT), tyrosine hydroxylase (TH), glutamic acid decarboxylase (GAD) and somatostatin-28 (SS-28). The first differentiating graft amacrine cells (cholinergic and dopaminergic) could be seen 1 week after transplantation (corresponding to postnatal day 1 = P1). The inner plexiform layer of the graft started to differentiate at 2 weeks (corresponding to P8) seen by HPC-1 and GAD staining. ChAT, TH and SS-28 immunostaining revealed an abnormal lamination pattern in the graft inner plexiform layer. Also by 2 weeks, the outer plexiform layers of the graft contained NF-immunoreactive horizontal cells. No NF-stained retinal ganglion cells could be observed in the graft. Five and 7 weeks after grafting, the transplants had obtained the same staining intensity with different markers as the host retina." @default.
• W2071427504 created "2016-06-24" @default.
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• W2071427504 date "1990-04-01" @default.
• W2071427504 modified "2023-10-16" @default.
• W2071427504 title "Neuronal markers in rat retinal grafts" @default.
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• W2071427504 doi "https://doi.org/10.1016/0165-3806(90)90123-g" @default.
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