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• W2071436280 abstract "Few phenomena are as suitable as perceptual multistability to demonstrate that the brain constructively interprets sensory input. Several studies have outlined the neural circuitry involved in generating perceptual inference but only more recently has the individual variability of this inferential process been appreciated. Studies of the interaction of evoked and ongoing neural activity show that inference itself is not merely a stimulus-triggered process but is related to the context of the current brain state into which the processing of external stimulation is embedded. As brain states fluctuate, so does perception of a given sensory input. In multistability, perceptual fluctuation rates are consistent for a given individual but vary considerably between individuals. There has been some evidence for a genetic basis for these individual differences and recent morphometric studies of parietal lobe regions have identified neuroanatomical substrates for individual variability in spontaneous switching behaviour. Moreover, disrupting the function of these latter regions by transcranial magnetic stimulation yields systematic interference effects on switching behaviour, further arguing for a causal role of these regions in perceptual inference. Together, these studies have advanced our understanding of the biological mechanisms by which the brain constructs the contents of consciousness from sensory input." @default.
• W2071436280 created "2016-06-24" @default.
• W2071436280 creator A5010246301 @default.
• W2071436280 creator A5066719885 @default.
• W2071436280 creator A5074881456 @default.
• W2071436280 date "2012-04-05" @default.
• W2071436280 modified "2023-10-01" @default.
• W2071436280 title "Variability of perceptual multistability: from brain state to individual trait" @default.
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• W2071436280 doi "https://doi.org/10.1098/rstb.2011.0367" @default.
• W2071436280 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3282312" @default.
• W2071436280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22371620" @default.
• W2071436280 hasPublicationYear "2012" @default.
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