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- W2071444608 endingPage "2312" @default.
- W2071444608 startingPage "2299" @default.
- W2071444608 abstract "Faithful segregation of chromosomes during mitosis and meiosis is the cornerstone process of life. Cohesin, a multi-protein complex conserved from yeast to human, plays a crucial role in this process by keeping the sister chromatids together from S-phase to anaphase onset during mitosis and meiosis. Technological advancements have discovered myriad functions of cohesin beyond its role in sister chromatid cohesion (SCC), such as transcription regulation, DNA repair, chromosome condensation, homolog pairing, monoorientation of sister kinetochore, etc. Here, we have focused on such functions of cohesin that are either independent of or dependent on its canonical role of sister chromatid cohesion. At the end, human diseases associated with malfunctioning of cohesin, albeit with mostly unperturbed sister chromatid cohesion, have been discussed." @default.
- W2071444608 created "2016-06-24" @default.
- W2071444608 creator A5007546431 @default.
- W2071444608 creator A5044845990 @default.
- W2071444608 creator A5045687571 @default.
- W2071444608 creator A5055725540 @default.
- W2071444608 date "2013-07-03" @default.
- W2071444608 modified "2023-09-25" @default.
- W2071444608 title "Cohesin: Functions beyond sister chromatid cohesion" @default.
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