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- W2071457092 abstract "Blood samples were obtained through the Blood Transfusion Service in Ireland in order to obtain information on the prevalence of asymptomatic B. burgdorferi infections and in an attempt to identify the type of habitat that presents the most risk of infection. Areas in the country were rated as low, medium or high risk based on the availability of suitable tick habitat, access to the public and the distribution of deer, the latter parameter being related to both the occurrence of rodent reservoir hosts and woodland recreational areas. Approximately 100 plasma samples from each of four areas were analysed for IgG anti-Borrelia antibodies by indirect immuno-fluorescence with a titre of 1 : 80 indicating a positive reaction in asymptomatic individuals. Prevalence figures of 15, 11, 8 and 5% were obtained for high, high/medium, medium/low and low risk areas respectively. No positive samples were detected in blood from an Icelandic population which is not exposed to I. ricinus bites. The overall subclinical prevalence (9.75%) is surprisingly high in view of the apparent rarity of clinical cases in Ireland, though under-diagnosis probably occurs. These results seem to indicate that farmland is less important than woodland as Lyme borreliosis habitat. If this is so, it is probably due to the presence in woodland of Apodemus sylvaticus, a putative reservoir host, and also to the use of sum areas for recreation at certain times of the year. Anhand von Blutproben des irischen Bluttransfusionsdienstes wurden Daten über das Vorkommen asymptomatischer B. burgdorferi-Infektionen und die Verbreitung von Hochrisiko-Regionen für diese Infektion gewonnen. Je nach Zecken-Vorkommen, öffentlicher Zugänglichkeit, Vorkommen von Hirsch und Reh sowie Nagetieren und von Waldgebieten, die der Erholung dienen, wurden die Regionen nach hohem, mittlerem und niedrigem Infektionsrisiko klassifiziert. Etwa 100 Plasmaproben aus jeder der 4 Regionen wurden auf Anti-Borrelia-IgG mit indirekter Immunfluoreszenz untersucht und Titer über 1: 80 als positive Reaktion bei asymptomatischen Individuen gewertet. Prävalenzwerte von 15, 11, 8 und 5 % wurden jeweils für die Regionen mit hohem, hohem bis mittlerem, mittlerem bis niedrigem und niedrigem Risiko erhalten. Keinerlei positive Seren waren bei Isländern zu finden, die den Bissen von Ixodes ricinus nicht ausgesetzt sind. In Irland ist die durchschnittliche subklinische Prävalenz von 9,75% überraschend hoch angesichts der Seltenheit klinisch manifester Fälle, selbst wenn man annimmt, daß zu wenige Fälle diagnostiziert werden. Die Ergebnisse lassen vermuten, daß Ackerland eine geringere Bedeutung als Lyme-Borreliose-Habitat zukommt als Wäldern, was möglicherweise mit der Waldmaus Apodemus sylvaticus, einem möglichen Erregerreservoir, und der Funktion der Wälder als Erholungsgebiete zu bestimmten Jahreszeiten zusammenhängt." @default.
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- W2071457092 date "1991-08-01" @default.
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- W2071457092 title "A Lyme Borreliosis Human Serosurvey of Asymptomatic Adults in Ireland" @default.
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- W2071457092 doi "https://doi.org/10.1016/s0934-8840(11)80304-x" @default.
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