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- W2071478811 endingPage "450" @default.
- W2071478811 startingPage "433" @default.
- W2071478811 abstract "ABSTRACT Tuberculosis (TB) is an international public health priority and kills almost two million people annually. TB is out of control in Africa due to increasing poverty and HIV coinfection, and drug‐resistant TB threatens to destabilize TB control efforts in several regions of the world. Existing diagnostic tools and therapeutic interventions for TB are suboptimal. Thus, new vaccines, immunotherapeutic interventions and diagnostic tools are urgently required to facilitate TB control efforts. An improved understanding of the immunopathogenesis of TB can facilitate the identification of correlates of immune protection, the design of effective vaccines, the rational selection of immunotherapeutic agents, the evaluation of new drug candidates, and drive the development of new immunodiagnostic tools. Here we review the immunology of TB with a focus on aspects that are clinically and therapeutically relevant. An immunologically orientated approach to tackling TB can only succeed with concurrent efforts to alleviate poverty and reduce the global burden of HIV." @default.
- W2071478811 created "2016-06-24" @default.
- W2071478811 creator A5026778987 @default.
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- W2071478811 creator A5034975443 @default.
- W2071478811 creator A5042973046 @default.
- W2071478811 creator A5056139536 @default.
- W2071478811 date "2010-03-29" @default.
- W2071478811 modified "2023-10-16" @default.
- W2071478811 title "The immunology of tuberculosis: From bench to bedside" @default.
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