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- W2071479791 abstract "Abstract The permeabilities of smectic mesophases (liposomes) to polar non-electrolytes were studied by measuring solute reflection coefficients. The measurements employed a rapid reaction stopped-flow apparatus. For a given solute the permeability is a function of the area per lipid molecule in the membrane. Thus the permeability of lecithin liposomes is decreased by incorporation of choleterol and increased by incorporation of phosphatidic acid. A comparison of different solutes shows that liposome permeabilty depends on solute size and lipid solubility in a manner similar to that observed for non-electrolyte permeation through synthetic polymers and some “non-porous” cell membranes. In the presence of 1 mM 2,4-dinitrophenol at pH 3.6 the permeability of lecithin liposomes to non-electrolytes decreases. A similar, but much smaller effect is observed in the presence of 5 mM Ca2+." @default.
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- W2071479791 date "1973-02-01" @default.
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- W2071479791 title "The permeability of lipid membranes to non-electrolytes" @default.
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- W2071479791 doi "https://doi.org/10.1016/0005-2736(73)90004-7" @default.
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