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• W2071495790 abstract "Pyrene-deoxynucleoside triphosphates (dPTPs), varying by the positioning of the aromatic system, were synthesized. Their ability to function as substrates for the Klenow fragment of Escherichia coli DNA polymerase I and the TdT polymerase was assessed. The dPTPs are all equally well tolerated by the Klenow fragment, and lead to elongation of up to 5 extra nucleotides of a ssDNA primer in a TdT-mediated reaction. The tailing efficiency of the dPTPs compares favorably to other less drastically modified dNTPs." @default.
• W2071495790 created "2016-06-24" @default.
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• W2071495790 date "2012-07-01" @default.
• W2071495790 modified "2023-09-23" @default.
• W2071495790 title "Polymerase incorporation of pyrene-nucleoside triphosphates" @default.
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• W2071495790 doi "https://doi.org/10.1016/j.bmcl.2012.04.101" @default.
• W2071495790 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22633686" @default.
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