FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071497838> ?p ?o ?g. }

• W2071497838 endingPage "1576" @default.
• W2071497838 startingPage "1571" @default.
• W2071497838 abstract "Enteric fever is the only bacterial infection of humans for which bone marrow examination is routinely recommended. A prospective study of the concentrations of bacteria in the bone marrow and their relationship to clinical features was conducted with 120 Vietnamese patients with suspected enteric fever, of whom 89 had confirmed typhoid fever. Ninety-three percent of the Salmonella enterica serovar Typhi samples isolated were resistant to ampicillin, chloramphenicol, and co-trimoxazole. For 81 patients with uncomplicated typhoid and satisfactory bone marrow aspirates, the number of serovar Typhi CFU in bone marrow aspirates was a median value of 9 (interquartile range [IQR], 1 to 85; range, 0.1 to 1,580) compared to 0.3 (IQR, 0.1 to 10; range, 0.1 to 399) CFU/ml in simultaneously sampled blood. The ratio of individual blood counts to bone marrow counts was 10 (IQR, 2.3 to 97.5). The number of bacteria in blood but not bone marrow was correlated inversely with the duration of preceding fever. Thus, with increasing duration of illness the ratio of bone marrow-to-blood bacterial concentrations increased; the median ratio was 4.8 (IQR, 1 to 27.5) during the first week compared with 158 (IQR, 60 to 397) during the third week. After lysing the host cells, the median ratio of viable bone marrow to blood increased, reflecting the higher concentration of intracellular serovar Typhi in the bone marrow. Effective antibiotic pretreatment had a significantly greater effect in reducing blood counts compared to bone marrow counts (P < 0.001). Thus, bacteria in the bone marrow of typhoid patients are less affected by antibiotic treatment than bacteria in the blood. The numbers of bacteria in bone marrow correlated negatively with the white blood cell (R = -0.3, P = 0.006) and platelet counts (R = -0.32, P = 0.01) and positively with fever clearance time after treatment (R = 0.4, P < 0.001). The bacterial load in bone marrow therefore may reflect the clinical course of the infection, and high levels may suppress neutrophil proliferation." @default.
• W2071497838 created "2016-06-24" @default.
• W2071497838 creator A5010264226 @default.
• W2071497838 creator A5028418409 @default.
• W2071497838 creator A5034097318 @default.
• W2071497838 creator A5040374998 @default.
• W2071497838 creator A5050718726 @default.
• W2071497838 creator A5050764672 @default.
• W2071497838 creator A5053003560 @default.
• W2071497838 creator A5055941702 @default.
• W2071497838 creator A5056799272 @default.
• W2071497838 creator A5067650157 @default.
• W2071497838 creator A5069545886 @default.
• W2071497838 creator A5078360219 @default.
• W2071497838 creator A5084217335 @default.
• W2071497838 date "2001-04-01" @default.
• W2071497838 modified "2023-10-16" @default.
• W2071497838 title "Quantitation of Bacteria in Bone Marrow from Patients with Typhoid Fever: Relationship between Counts and Clinical Features" @default.
• W2071497838 cites W1736980676 @default.
• W2071497838 cites W1768824435 @default.
• W2071497838 cites W1884351988 @default.
• W2071497838 cites W1900247611 @default.
• W2071497838 cites W1985358754 @default.
• W2071497838 cites W2016968175 @default.
• W2071497838 cites W2051688009 @default.
• W2071497838 cites W2064393979 @default.
• W2071497838 cites W2070530724 @default.
• W2071497838 cites W2072290872 @default.
• W2071497838 cites W2091069613 @default.
• W2071497838 cites W2109626244 @default.
• W2071497838 cites W2129441157 @default.
• W2071497838 cites W2129938023 @default.
• W2071497838 cites W2137304822 @default.
• W2071497838 cites W2141754798 @default.
• W2071497838 cites W2153796695 @default.
• W2071497838 cites W2158238171 @default.
• W2071497838 cites W2409999187 @default.
• W2071497838 cites W2418185171 @default.
• W2071497838 cites W4242074223 @default.
• W2071497838 cites W56622060 @default.
• W2071497838 doi "https://doi.org/10.1128/jcm.39.4.1571-1576.2001" @default.
• W2071497838 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/87972" @default.
• W2071497838 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11283089" @default.
• W2071497838 hasPublicationYear "2001" @default.
• W2071497838 type Work @default.
• W2071497838 sameAs 2071497838 @default.
• W2071497838 citedByCount "177" @default.
• W2071497838 countsByYear W20714978382012 @default.
• W2071497838 countsByYear W20714978382013 @default.
• W2071497838 countsByYear W20714978382014 @default.
• W2071497838 countsByYear W20714978382015 @default.
• W2071497838 countsByYear W20714978382016 @default.
• W2071497838 countsByYear W20714978382017 @default.
• W2071497838 countsByYear W20714978382018 @default.
• W2071497838 countsByYear W20714978382019 @default.
• W2071497838 countsByYear W20714978382020 @default.
• W2071497838 countsByYear W20714978382021 @default.
• W2071497838 countsByYear W20714978382022 @default.
• W2071497838 countsByYear W20714978382023 @default.
• W2071497838 crossrefType "journal-article" @default.
• W2071497838 hasAuthorship W2071497838A5010264226 @default.
• W2071497838 hasAuthorship W2071497838A5028418409 @default.
• W2071497838 hasAuthorship W2071497838A5034097318 @default.
• W2071497838 hasAuthorship W2071497838A5040374998 @default.
• W2071497838 hasAuthorship W2071497838A5050718726 @default.
• W2071497838 hasAuthorship W2071497838A5050764672 @default.
• W2071497838 hasAuthorship W2071497838A5053003560 @default.
• W2071497838 hasAuthorship W2071497838A5055941702 @default.
• W2071497838 hasAuthorship W2071497838A5056799272 @default.
• W2071497838 hasAuthorship W2071497838A5067650157 @default.
• W2071497838 hasAuthorship W2071497838A5069545886 @default.
• W2071497838 hasAuthorship W2071497838A5078360219 @default.
• W2071497838 hasAuthorship W2071497838A5084217335 @default.
• W2071497838 hasBestOaLocation W20714978382 @default.
• W2071497838 hasConcept C104317684 @default.
• W2071497838 hasConcept C119060515 @default.
• W2071497838 hasConcept C126322002 @default.
• W2071497838 hasConcept C142724271 @default.
• W2071497838 hasConcept C203014093 @default.
• W2071497838 hasConcept C2779443120 @default.
• W2071497838 hasConcept C2780007613 @default.
• W2071497838 hasConcept C2994552716 @default.
• W2071497838 hasConcept C501593827 @default.
• W2071497838 hasConcept C520601542 @default.
• W2071497838 hasConcept C547475151 @default.
• W2071497838 hasConcept C55493867 @default.
• W2071497838 hasConcept C71924100 @default.
• W2071497838 hasConcept C86803240 @default.
• W2071497838 hasConcept C89423630 @default.
• W2071497838 hasConcept C90924648 @default.
• W2071497838 hasConceptScore W2071497838C104317684 @default.
• W2071497838 hasConceptScore W2071497838C119060515 @default.
• W2071497838 hasConceptScore W2071497838C126322002 @default.
• W2071497838 hasConceptScore W2071497838C142724271 @default.
• W2071497838 hasConceptScore W2071497838C203014093 @default.
• W2071497838 hasConceptScore W2071497838C2779443120 @default.
• W2071497838 hasConceptScore W2071497838C2780007613 @default.
• W2071497838 hasConceptScore W2071497838C2994552716 @default.

• next