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- W2071544009 endingPage "523" @default.
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- W2071544009 abstract "I. Reliability of the results of bio-medical research clearly depends upon the animals used showing as standard responses as is possible. 2. The majority of animals used in this field are small, homoiothermic mammals which have sensitive and strong homeostatic mechanisms. If a change in ambient conditions is of sufficient magnitude to unbalance homeostasis, then the neuroendocrine system is stimulated so as to restore it, and this can interfere with the response to test conditions or agents. 3. The homeostatic effectors involved are diverse and can include both physiological and behavioural changes in the animal. These can affect metabolic rate, body temperature, activity, food consumption, hormone concentration, wake/sleep patterns, maturation, posture, lactation and many other bodily functions. Any of these changes is potentially capable of influencing experimental results. 4. The evidence presented shows how environmental factors may affect the outcome of experiments in the fields of animal behaviour, cancer research, immunology, pathology, pharmacology, psychology, reproduction, teratology and toxicology; particular attention is paid to the effects of ambient temperature, relative humidity, air movement and quality, light and sound. 5. While a constant, reproducible environment would be ideal, there is little possibility of controlling all the variables; nevertheless all investigators should minimize those environmental variables that have been shown to be important. 6. To enable other investigators to repeat experiments or carry out comparative studies, environmental conditions pertaining during an experiment should be adequately described in any publications." @default.
- W2071544009 created "2016-06-24" @default.
- W2071544009 creator A5040239684 @default.
- W2071544009 date "1982-08-01" @default.
- W2071544009 modified "2023-10-16" @default.
- W2071544009 title "ENVIRONMENTAL EFFECTS ON ANIMALS USED IN BIOMEDICAL RESEARCH" @default.
- W2071544009 cites W101313431 @default.
- W2071544009 cites W1493447394 @default.
- W2071544009 cites W1927402810 @default.
- W2071544009 cites W1964110865 @default.
- W2071544009 cites W1965317620 @default.
- W2071544009 cites W1965407987 @default.
- W2071544009 cites W1965448940 @default.
- W2071544009 cites W1970635333 @default.
- W2071544009 cites W1977340398 @default.
- W2071544009 cites W1978555946 @default.
- W2071544009 cites W1979218266 @default.
- W2071544009 cites W1981293138 @default.
- W2071544009 cites W1982437848 @default.
- W2071544009 cites W1983662452 @default.
- W2071544009 cites W1983767610 @default.
- W2071544009 cites W1985621616 @default.
- W2071544009 cites W1988851344 @default.
- W2071544009 cites W1992232764 @default.
- W2071544009 cites W1992240306 @default.
- W2071544009 cites W1993185766 @default.
- W2071544009 cites W1997820474 @default.
- W2071544009 cites W1998448461 @default.
- W2071544009 cites W1999423554 @default.
- W2071544009 cites W2000642437 @default.
- W2071544009 cites W2004281480 @default.
- W2071544009 cites W2005793461 @default.
- W2071544009 cites W2005989346 @default.
- W2071544009 cites W2006326380 @default.
- W2071544009 cites W2012332688 @default.
- W2071544009 cites W2014020479 @default.
- W2071544009 cites W2014226598 @default.
- W2071544009 cites W2016415256 @default.
- W2071544009 cites W2019533444 @default.
- W2071544009 cites W2025088299 @default.
- W2071544009 cites W2025275658 @default.
- W2071544009 cites W202562869 @default.
- W2071544009 cites W2028846070 @default.
- W2071544009 cites W2029204922 @default.
- W2071544009 cites W2033924138 @default.
- W2071544009 cites W2036109321 @default.
- W2071544009 cites W2037019372 @default.
- W2071544009 cites W2037440438 @default.
- W2071544009 cites W2039262906 @default.
- W2071544009 cites W2039969555 @default.
- W2071544009 cites W2040476714 @default.
- W2071544009 cites W2041738914 @default.
- W2071544009 cites W2043149567 @default.
- W2071544009 cites W2044063013 @default.
- W2071544009 cites W2049906709 @default.
- W2071544009 cites W2054377201 @default.
- W2071544009 cites W2058758581 @default.
- W2071544009 cites W2060464022 @default.
- W2071544009 cites W2063012976 @default.
- W2071544009 cites W2070375494 @default.
- W2071544009 cites W2072306270 @default.
- W2071544009 cites W2078016456 @default.
- W2071544009 cites W2079667700 @default.
- W2071544009 cites W2082473883 @default.
- W2071544009 cites W2083533622 @default.
- W2071544009 cites W2087801236 @default.
- W2071544009 cites W2088702070 @default.
- W2071544009 cites W2088917071 @default.
- W2071544009 cites W2089275386 @default.
- W2071544009 cites W2090521760 @default.
- W2071544009 cites W2095507070 @default.
- W2071544009 cites W2095867471 @default.
- W2071544009 cites W2106356527 @default.
- W2071544009 cites W2111245372 @default.
- W2071544009 cites W2112057254 @default.
- W2071544009 cites W2113157043 @default.
- W2071544009 cites W2117418296 @default.
- W2071544009 cites W2123121254 @default.
- W2071544009 cites W2125813431 @default.
- W2071544009 cites W2128772072 @default.
- W2071544009 cites W2130501565 @default.
- W2071544009 cites W2132518862 @default.
- W2071544009 cites W2136029455 @default.
- W2071544009 cites W2141953979 @default.
- W2071544009 cites W2145280616 @default.
- W2071544009 cites W2153195274 @default.
- W2071544009 cites W2157197782 @default.
- W2071544009 cites W2167578335 @default.
- W2071544009 cites W2252286285 @default.
- W2071544009 cites W2269168004 @default.
- W2071544009 cites W2315072571 @default.
- W2071544009 cites W2315609562 @default.
- W2071544009 cites W2316540876 @default.
- W2071544009 cites W2326647080 @default.
- W2071544009 cites W2332792347 @default.
- W2071544009 cites W2333862634 @default.
- W2071544009 cites W2335250773 @default.
- W2071544009 cites W2405123243 @default.