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- W2071554281 endingPage "484" @default.
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- W2071554281 abstract "While the various internal organs of vertebrates display many obvious left-right asymmetries in their location and/or morphology, external features exhibit a high degree of bilateral symmetry. How this external bilateral symmetry is established during development is largely unknown. In this review, we explore several mechanisms, in place during development, that regulate the final size of the limb. These mechanisms rely on the presence of positive signaling feedback loops during limb bud growth. Through the activity of these signaling loops and their eventual breakdown when the limb bud has reached a certain size, bilateral symmetry can be achieved." @default.
- W2071554281 created "2016-06-24" @default.
- W2071554281 creator A5014300544 @default.
- W2071554281 creator A5062835705 @default.
- W2071554281 date "2009-06-01" @default.
- W2071554281 modified "2023-09-23" @default.
- W2071554281 title "Achieving bilateral symmetry during vertebrate limb development" @default.
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- W2071554281 doi "https://doi.org/10.1016/j.semcdb.2008.10.011" @default.
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