Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071569129> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2071569129 abstract "Growth hormone (GH) is the most frequently used treatment in children with idiopathic short stature (ISS). Aromatase inhibitor (AI) therapy is still in an experimental state, and both final height (FH) and long-term efficacy data in ISS have not been published. We present a 14.5-year-old boy with ISS and a height of 142.7 cm [standard deviation score (SDS) –2.79]. Based on the baseline bone age (BA) of 13.5–14 years, his predicted adult height (PAH) by Bayley/Pinneau was 154 cm (SDS –3.77)–158.2 (SDS –3.15). After a 5-year letrozole monotherapy, FH was 169 cm (SDS –1.57) showing a height difference between PAH and FH from 10.8 to 15 cm. No permanent side effects of the medication have been observed. Both a transient occurrence and a spontaneous recovery of decreased bone mineral apparent density were seen, verified by dual-energy X-ray absorptiometry. Spinal magnetic resonance imaging revealed no vertebral abnormalities. AI therapy might be an effective and low-cost alternative to the use of GH. Further controlled trials should prove efficacy and safety of long-term AI therapy in boys with ISS." @default.
- W2071569129 created "2016-06-24" @default.
- W2071569129 creator A5011977613 @default.
- W2071569129 creator A5012423348 @default.
- W2071569129 creator A5020652960 @default.
- W2071569129 creator A5065581845 @default.
- W2071569129 creator A5089289989 @default.
- W2071569129 creator A5090323737 @default.
- W2071569129 date "2012-01-01" @default.
- W2071569129 modified "2023-09-26" @default.
- W2071569129 title "Marked increase of final height by long-term aromatase inhibition in a boy with idiopathic short stature" @default.
- W2071569129 doi "https://doi.org/10.1515/jpem-2011-0435" @default.
- W2071569129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22876562" @default.
- W2071569129 hasPublicationYear "2012" @default.
- W2071569129 type Work @default.
- W2071569129 sameAs 2071569129 @default.
- W2071569129 citedByCount "8" @default.
- W2071569129 countsByYear W20715691292013 @default.
- W2071569129 countsByYear W20715691292015 @default.
- W2071569129 countsByYear W20715691292019 @default.
- W2071569129 countsByYear W20715691292020 @default.
- W2071569129 countsByYear W20715691292021 @default.
- W2071569129 countsByYear W20715691292023 @default.
- W2071569129 crossrefType "journal-article" @default.
- W2071569129 hasAuthorship W2071569129A5011977613 @default.
- W2071569129 hasAuthorship W2071569129A5012423348 @default.
- W2071569129 hasAuthorship W2071569129A5020652960 @default.
- W2071569129 hasAuthorship W2071569129A5065581845 @default.
- W2071569129 hasAuthorship W2071569129A5089289989 @default.
- W2071569129 hasAuthorship W2071569129A5090323737 @default.
- W2071569129 hasBestOaLocation W20715691292 @default.
- W2071569129 hasConcept C121608353 @default.
- W2071569129 hasConcept C126322002 @default.
- W2071569129 hasConcept C126838900 @default.
- W2071569129 hasConcept C126894567 @default.
- W2071569129 hasConcept C143409427 @default.
- W2071569129 hasConcept C187212893 @default.
- W2071569129 hasConcept C2776166826 @default.
- W2071569129 hasConcept C2776541429 @default.
- W2071569129 hasConcept C2776886416 @default.
- W2071569129 hasConcept C2777871287 @default.
- W2071569129 hasConcept C2778504769 @default.
- W2071569129 hasConcept C2778754045 @default.
- W2071569129 hasConcept C2778812593 @default.
- W2071569129 hasConcept C2984496839 @default.
- W2071569129 hasConcept C2989005 @default.
- W2071569129 hasConcept C530470458 @default.
- W2071569129 hasConcept C71315377 @default.
- W2071569129 hasConcept C71924100 @default.
- W2071569129 hasConcept C89551170 @default.
- W2071569129 hasConceptScore W2071569129C121608353 @default.
- W2071569129 hasConceptScore W2071569129C126322002 @default.
- W2071569129 hasConceptScore W2071569129C126838900 @default.
- W2071569129 hasConceptScore W2071569129C126894567 @default.
- W2071569129 hasConceptScore W2071569129C143409427 @default.
- W2071569129 hasConceptScore W2071569129C187212893 @default.
- W2071569129 hasConceptScore W2071569129C2776166826 @default.
- W2071569129 hasConceptScore W2071569129C2776541429 @default.
- W2071569129 hasConceptScore W2071569129C2776886416 @default.
- W2071569129 hasConceptScore W2071569129C2777871287 @default.
- W2071569129 hasConceptScore W2071569129C2778504769 @default.
- W2071569129 hasConceptScore W2071569129C2778754045 @default.
- W2071569129 hasConceptScore W2071569129C2778812593 @default.
- W2071569129 hasConceptScore W2071569129C2984496839 @default.
- W2071569129 hasConceptScore W2071569129C2989005 @default.
- W2071569129 hasConceptScore W2071569129C530470458 @default.
- W2071569129 hasConceptScore W2071569129C71315377 @default.
- W2071569129 hasConceptScore W2071569129C71924100 @default.
- W2071569129 hasConceptScore W2071569129C89551170 @default.
- W2071569129 hasIssue "5-6" @default.
- W2071569129 hasLocation W20715691291 @default.
- W2071569129 hasLocation W20715691292 @default.
- W2071569129 hasLocation W20715691293 @default.
- W2071569129 hasOpenAccess W2071569129 @default.
- W2071569129 hasPrimaryLocation W20715691291 @default.
- W2071569129 hasRelatedWork W2057333959 @default.
- W2071569129 hasRelatedWork W2071569129 @default.
- W2071569129 hasRelatedWork W2117443814 @default.
- W2071569129 hasRelatedWork W2157097180 @default.
- W2071569129 hasRelatedWork W2178621426 @default.
- W2071569129 hasRelatedWork W2529804209 @default.
- W2071569129 hasRelatedWork W2587798057 @default.
- W2071569129 hasRelatedWork W3029468115 @default.
- W2071569129 hasRelatedWork W3048848035 @default.
- W2071569129 hasRelatedWork W4252325302 @default.
- W2071569129 hasVolume "25" @default.
- W2071569129 isParatext "false" @default.
- W2071569129 isRetracted "false" @default.
- W2071569129 magId "2071569129" @default.
- W2071569129 workType "article" @default.