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- W2071570254 abstract "Abstract Axonal transport of putrescine and the polyamines in normal and transected motor axons of adult rat sciatic nerves was studied. [ 3 H]Putrescine injected into the ventral horn region of the spinal cord was not transported distally along the course of the nerve as a function of time. l -[ 3 H]ornithine, the immediate precursor of putrescine, when injected into the ventral horn of the spinal cord, was followed by rapid axonal transport of acid-insoluble material, but no transport of acid-soluble material, such as putrescine or the polyamines, was detected despite the demonstration that radioactive spermidine was synthesized at the site of the l -[ 3 H]ornithine injection in the spinal cord. Furthermore, acid-soluble radioactive material failed to accumulate proximal to the site of a ligature of the sciatic nerve in acute and chronic experiments. Ligation of the sciatic nerve also failed to cause an accumulation of endogenous putrescine proximal to the ligature. The data showed no evidence for fast axonal transport of putrescine and the polyamines in normal and transected motor axons of the sciatic nerve in adult rats." @default.
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- W2071570254 date "1979-02-01" @default.
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- W2071570254 title "Axonal transport of polyamines: A reappraisal" @default.
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- W2071570254 doi "https://doi.org/10.1016/0014-4886(79)90127-4" @default.
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