FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071574407> ?p ?o ?g. }

• W2071574407 endingPage "186" @default.
• W2071574407 startingPage "176" @default.
• W2071574407 abstract "Patients with vitamin A/retinol deficiency are shown to be prone to infections and to suffer from increased inflammation, effects which can be remedied by vitamin A supplements. We aimed to study how human monocytes from the peripheral venous blood of healthy donors acted within the initial hours after adherence and exposure to bacterial endotoxin in the presence or absence of the 9-cis-isomer of retinoic acid (9cisRA). We found that adherent human monocytes were dominated by the CD14dimCD16+ subtype. Pretreatment with 9cisRA for 1 h significantly decreased lipopolysaccharide (LPS)-induced mRNA expression and protein release of tumor necrosis factor (TNF)α, interleukin (IL)-6 and chemokine ligands (CCL)3 and CCL4. In contrast, treatment with 9cisRA rapidly enhanced the production of monocyte chemoattractive protein/CCL2. 9cisRA treatment also led to enhanced migration of classical CD14high monocytes in a transwell in vitro system. We conclude that 9cisRA treatment of human adherent monocytes attenuates the inflammatory responses to LPS and induces the attraction of classical monocytes, a feature which may help explain why supplements administered to vitamin A-deficient patients counteract inflammation and increases the ability to fight infections." @default.
• W2071574407 created "2016-06-24" @default.
• W2071574407 creator A5004123023 @default.
• W2071574407 creator A5007133595 @default.
• W2071574407 creator A5015104172 @default.
• W2071574407 creator A5046707135 @default.
• W2071574407 creator A5057304546 @default.
• W2071574407 creator A5075417155 @default.
• W2071574407 date "2011-12-29" @default.
• W2071574407 modified "2023-09-26" @default.
• W2071574407 title "9-cis Retinoic Acid Inhibits Inflammatory Responses of Adherent Monocytes and Increases Their Ability to Induce Classical Monocyte Migration" @default.
• W2071574407 cites W101740868 @default.
• W2071574407 cites W1523820703 @default.
• W2071574407 cites W1529144074 @default.
• W2071574407 cites W1888837644 @default.
• W2071574407 cites W1974749956 @default.
• W2071574407 cites W1981243375 @default.
• W2071574407 cites W1984509210 @default.
• W2071574407 cites W1991026693 @default.
• W2071574407 cites W1995525413 @default.
• W2071574407 cites W2001473459 @default.
• W2071574407 cites W2003716616 @default.
• W2071574407 cites W2004070471 @default.
• W2071574407 cites W2005229619 @default.
• W2071574407 cites W2017578370 @default.
• W2071574407 cites W2017719948 @default.
• W2071574407 cites W2022808441 @default.
• W2071574407 cites W2026526608 @default.
• W2071574407 cites W2042052456 @default.
• W2071574407 cites W2046208657 @default.
• W2071574407 cites W2048732925 @default.
• W2071574407 cites W2049983202 @default.
• W2071574407 cites W2052429604 @default.
• W2071574407 cites W2062308880 @default.
• W2071574407 cites W2063532971 @default.
• W2071574407 cites W2082107944 @default.
• W2071574407 cites W2091128689 @default.
• W2071574407 cites W2091544680 @default.
• W2071574407 cites W2108622639 @default.
• W2071574407 cites W2112701647 @default.
• W2071574407 cites W2116422482 @default.
• W2071574407 cites W2118842826 @default.
• W2071574407 cites W2130595129 @default.
• W2071574407 cites W2135328964 @default.
• W2071574407 cites W2135919238 @default.
• W2071574407 cites W2145508404 @default.
• W2071574407 cites W2158231545 @default.
• W2071574407 cites W92308566 @default.
• W2071574407 doi "https://doi.org/10.1159/000332375" @default.
• W2071574407 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6741473" @default.
• W2071574407 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22213773" @default.
• W2071574407 hasPublicationYear "2011" @default.
• W2071574407 type Work @default.
• W2071574407 sameAs 2071574407 @default.
• W2071574407 citedByCount "16" @default.
• W2071574407 countsByYear W20715744072012 @default.
• W2071574407 countsByYear W20715744072013 @default.
• W2071574407 countsByYear W20715744072014 @default.
• W2071574407 countsByYear W20715744072015 @default.
• W2071574407 countsByYear W20715744072016 @default.
• W2071574407 countsByYear W20715744072020 @default.
• W2071574407 countsByYear W20715744072021 @default.
• W2071574407 countsByYear W20715744072022 @default.
• W2071574407 crossrefType "journal-article" @default.
• W2071574407 hasAuthorship W2071574407A5004123023 @default.
• W2071574407 hasAuthorship W2071574407A5007133595 @default.
• W2071574407 hasAuthorship W2071574407A5015104172 @default.
• W2071574407 hasAuthorship W2071574407A5046707135 @default.
• W2071574407 hasAuthorship W2071574407A5057304546 @default.
• W2071574407 hasAuthorship W2071574407A5075417155 @default.
• W2071574407 hasBestOaLocation W20715744071 @default.
• W2071574407 hasConcept C101666144 @default.
• W2071574407 hasConcept C102124568 @default.
• W2071574407 hasConcept C104317684 @default.
• W2071574407 hasConcept C13373296 @default.
• W2071574407 hasConcept C137061746 @default.
• W2071574407 hasConcept C178790620 @default.
• W2071574407 hasConcept C17991360 @default.
• W2071574407 hasConcept C185592680 @default.
• W2071574407 hasConcept C202751555 @default.
• W2071574407 hasConcept C203014093 @default.
• W2071574407 hasConcept C2776914184 @default.
• W2071574407 hasConcept C2776940978 @default.
• W2071574407 hasConcept C2777359374 @default.
• W2071574407 hasConcept C2778754761 @default.
• W2071574407 hasConcept C2779963572 @default.
• W2071574407 hasConcept C2781121885 @default.
• W2071574407 hasConcept C2781184567 @default.
• W2071574407 hasConcept C55493867 @default.
• W2071574407 hasConcept C71924100 @default.
• W2071574407 hasConceptScore W2071574407C101666144 @default.
• W2071574407 hasConceptScore W2071574407C102124568 @default.
• W2071574407 hasConceptScore W2071574407C104317684 @default.
• W2071574407 hasConceptScore W2071574407C13373296 @default.
• W2071574407 hasConceptScore W2071574407C137061746 @default.
• W2071574407 hasConceptScore W2071574407C178790620 @default.
• W2071574407 hasConceptScore W2071574407C17991360 @default.
• W2071574407 hasConceptScore W2071574407C185592680 @default.

• next