FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071576884> ?p ?o ?g. }

• W2071576884 endingPage "314" @default.
• W2071576884 startingPage "308" @default.
• W2071576884 abstract "Low high-density lipoprotein (HDL) cholesterol is well-established as a negative risk factor for coronary artery disease (CAD) and its anti-oxidant property has been attributed mainly to the HDL-bound enzyme paraoxonase-1 (PON-1). Recently, myeloperoxidase (MPO), a pro-oxidant enzyme released from activated neutrophils, has been shown to alter the atheroprotective function of HDL to a dysfunctional form. This study investigated the relationship between plasma MPO and serum PON-1 levels in patients with stable (SAP) and unstable angina pectoris (UAP).Plasma MPO levels and serum PON-1 concentration/activity were measured in patients with SAP (n = 226), UAP (n = 151) and in control subjects (n = 99).Plasma MPO levels in UAP patients were significantly higher than those in SAP patients or in control subjects (UAP, 21.6[16.7-44.6]; SAP, 19.3[15.7-29.1]; control, 15.9[14.7-18.7] ng/mL; P < 0.0001). Serum PON-1 concentrations in UAP and SAP patients were significantly lower than those in control subjects (UAP, 55.6[45.9-69.7]; SAP, 55.0[46.9-64.9]; control, 62.5[51.1-78.8] μg/mL; P = 0.0002). Plasma MPO levels showed a weak inverse correlation with serum PON-1 concentrations in all subjects (R = -0.163, P < 0.0005). Moreover, in women, plasma MPO levels showed a significant inverse correlation with serum PON-1 concentrations and PON-arylesterase activity in SAP (concentration: R = -0.537, P < 0.0001; arylesterase-activity: R = -0.469, P < 0.001) and UAP (concentration: R = -0.340, P < 0.05; arylesterase-activity: R = -0.350, P < 0.05) patients, but not in men.This study demonstrates that plasma MPO levels have a significant inverse correlation with PON-1 levels, especially in women, in SAP and UAP patients, and suggests that an imbalance between pro-oxidants and anti-oxidants may contribute to the progression of coronary plaque instability." @default.
• W2071576884 created "2016-06-24" @default.
• W2071576884 creator A5001741126 @default.
• W2071576884 creator A5004162629 @default.
• W2071576884 creator A5011964941 @default.
• W2071576884 creator A5022118293 @default.
• W2071576884 creator A5026949524 @default.
• W2071576884 creator A5041133341 @default.
• W2071576884 creator A5044924496 @default.
• W2071576884 creator A5047738959 @default.
• W2071576884 creator A5051487294 @default.
• W2071576884 creator A5065329060 @default.
• W2071576884 creator A5070959662 @default.
• W2071576884 creator A5074241677 @default.
• W2071576884 creator A5077074817 @default.
• W2071576884 creator A5086848779 @default.
• W2071576884 date "2013-12-01" @default.
• W2071576884 modified "2023-10-16" @default.
• W2071576884 title "Gender-specific correlation between plasma myeloperoxidase levels and serum high-density lipoprotein-associated paraoxonase-1 levels in patients with stable and unstable coronary artery disease" @default.
• W2071576884 cites W1561615847 @default.
• W2071576884 cites W1586022876 @default.
• W2071576884 cites W1975149587 @default.
• W2071576884 cites W1978617840 @default.
• W2071576884 cites W1983394870 @default.
• W2071576884 cites W1998088784 @default.
• W2071576884 cites W1998662899 @default.
• W2071576884 cites W1999487324 @default.
• W2071576884 cites W2006137455 @default.
• W2071576884 cites W2007259601 @default.
• W2071576884 cites W2015635131 @default.
• W2071576884 cites W2031043834 @default.
• W2071576884 cites W2042474992 @default.
• W2071576884 cites W2048607595 @default.
• W2071576884 cites W2049993340 @default.
• W2071576884 cites W2054251943 @default.
• W2071576884 cites W2063422088 @default.
• W2071576884 cites W2064373810 @default.
• W2071576884 cites W2067440555 @default.
• W2071576884 cites W2074678197 @default.
• W2071576884 cites W2079307913 @default.
• W2071576884 cites W2083168568 @default.
• W2071576884 cites W2084075677 @default.
• W2071576884 cites W2093687473 @default.
• W2071576884 cites W2096664466 @default.
• W2071576884 cites W2101714885 @default.
• W2071576884 cites W2107952252 @default.
• W2071576884 cites W2109539718 @default.
• W2071576884 cites W2109863092 @default.
• W2071576884 cites W2114490800 @default.
• W2071576884 cites W2121811672 @default.
• W2071576884 cites W2129413805 @default.
• W2071576884 cites W2134293572 @default.
• W2071576884 cites W2134343469 @default.
• W2071576884 cites W2134850153 @default.
• W2071576884 cites W2141409038 @default.
• W2071576884 cites W2143954917 @default.
• W2071576884 cites W2152089216 @default.
• W2071576884 cites W2161579754 @default.
• W2071576884 cites W2162204993 @default.
• W2071576884 cites W2164720318 @default.
• W2071576884 cites W2316877966 @default.
• W2071576884 cites W4230038264 @default.
• W2071576884 doi "https://doi.org/10.1016/j.atherosclerosis.2013.08.037" @default.
• W2071576884 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24267244" @default.
• W2071576884 hasPublicationYear "2013" @default.
• W2071576884 type Work @default.
• W2071576884 sameAs 2071576884 @default.
• W2071576884 citedByCount "30" @default.
• W2071576884 countsByYear W20715768842013 @default.
• W2071576884 countsByYear W20715768842015 @default.
• W2071576884 countsByYear W20715768842016 @default.
• W2071576884 countsByYear W20715768842017 @default.
• W2071576884 countsByYear W20715768842018 @default.
• W2071576884 countsByYear W20715768842019 @default.
• W2071576884 countsByYear W20715768842020 @default.
• W2071576884 countsByYear W20715768842021 @default.
• W2071576884 countsByYear W20715768842022 @default.
• W2071576884 countsByYear W20715768842023 @default.
• W2071576884 crossrefType "journal-article" @default.
• W2071576884 hasAuthorship W2071576884A5001741126 @default.
• W2071576884 hasAuthorship W2071576884A5004162629 @default.
• W2071576884 hasAuthorship W2071576884A5011964941 @default.
• W2071576884 hasAuthorship W2071576884A5022118293 @default.
• W2071576884 hasAuthorship W2071576884A5026949524 @default.
• W2071576884 hasAuthorship W2071576884A5041133341 @default.
• W2071576884 hasAuthorship W2071576884A5044924496 @default.
• W2071576884 hasAuthorship W2071576884A5047738959 @default.
• W2071576884 hasAuthorship W2071576884A5051487294 @default.
• W2071576884 hasAuthorship W2071576884A5065329060 @default.
• W2071576884 hasAuthorship W2071576884A5070959662 @default.
• W2071576884 hasAuthorship W2071576884A5074241677 @default.
• W2071576884 hasAuthorship W2071576884A5077074817 @default.
• W2071576884 hasAuthorship W2071576884A5086848779 @default.
• W2071576884 hasConcept C104317684 @default.
• W2071576884 hasConcept C126322002 @default.
• W2071576884 hasConcept C134018914 @default.
• W2071576884 hasConcept C135763542 @default.
• W2071576884 hasConcept C185592680 @default.

• next