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- W2071585344 abstract "Considerable progress has been made in the treatment of newly diagnosed childhood acute lymphoblastic leukemia. With the use of intensive, risk-stratified multiagent chemotherapeutic protocols, over 80% of patients can hope to be long-term survivors. However, despite optimal treatment, about 20% of patients relapse. The treatment of these children poses a major challenge. The prognosis of these patients depends on a number of factors including time since diagnosis, the site of relapse and immunophenotype. The choice of postinduction therapy depends on these prognostic factors. Considerable work has been done to identify the subgroups of relapsed patients whose outcomes are significantly altered by allogeneic bone marrow transplant. In our scenario, the limited availability of allogeneic bone marrow transplant due to a host of factors renders the management of these children even more challenging." @default.
- W2071585344 created "2016-06-24" @default.
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- W2071585344 date "2011-12-01" @default.
- W2071585344 modified "2023-09-26" @default.
- W2071585344 title "Guidelines for the management of relapsed acute lymphoblastic leukemia in childhood" @default.
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- W2071585344 doi "https://doi.org/10.1016/s0976-0016(11)60011-2" @default.
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