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• W2071628152 abstract "Information processing in the medial frontal cortex is often said to be modulated in pathological conditions or by individual traits. This has been observed in neuroimaging and event-related potential studies centered in particular on midcingulate cortex (MCC) functions. This region of the brain is characterized by considerable intersubject morphological variability. Whereas in a subset of hemispheres only a single cingulate sulcus (cgs) is present, a majority of hemispheres exhibit an additional sulcus referred to as the paracingulate sulcus (pcgs). The present functional magnetic resonance imaging study defined the relationship between the local morphology of the cingulate/paracingulate sulcal complex and feedback-related activity. Human subjects performed a trial-and-error learning task in which they had to discover which one of a set of abstract stimuli was the best option. Feedback was provided by means of fruit juice, as in studies with monkeys. A subject-by-subject analysis revealed that the feedback-related activity during exploration was systematically located in the cgs when no pcgs was observed, but in the pcgs when the latter sulcus was present. The activations had the same functional signature when located in either the cgs or in the pcgs, confirming that both regions were homologues. Together, the results show that the location of feedback-related MCC activity can be predicted from morphological features of the cingulate/paracingulate complex." @default.
• W2071628152 created "2016-06-24" @default.
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• W2071628152 date "2013-01-30" @default.
• W2071628152 modified "2023-10-14" @default.
• W2071628152 title "The Location of Feedback-Related Activity in the Midcingulate Cortex Is Predicted by Local Morphology" @default.
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• W2071628152 doi "https://doi.org/10.1523/jneurosci.2779-12.2013" @default.
• W2071628152 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6619107" @default.
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