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• W2071639384 abstract "To elucidate the relationship between MetS and ischemic stroke, we evaluated the association of MetS and individual components with frequency of ischemic stroke lesions and investigated the independent associations between them in acute ischemic stroke patients.We evaluated 370 acute ischemic stroke patients who underwent brain magnetic resonance (MR) imaging and MR angiography. The stroke subgroups were categorized as intracranial large artery atherosclerosis (IC-LAA, n=151), extracranial large artery atherosclerosis (EC-LAA, n=35), and nonatherosclerosis (NA, n=184). MetS was defined using the criteria of the International Diabetes Federation.Patients with IC-LAA group showed a higher rate of MetS and previous ischemic lesions (predominantly deep gray/white matter) than those with EC-LAA and NA (all P<0.001). The number of previous ischemic lesions showed a tendency to increase as the number of MetS components increased in the IC-LAA group (P=0.004). In the IC-LAA group, age (OR, 1.04) and MetS (OR, 3.28) were independently associated with previous ischemic lesions (all P<0.001), which was prominent with more severe MetS components after adjustment for risk factors (P<0.001). Among the component conditions, high blood pressure, impaired fasting glucose, and abdominal obesity were more associated with previous ischemic lesions (all P<0.001) than low high-density lipoprotein and high triglyceride levels (P=0.010 and 0.028, respectively).Our study showed a strong association between MetS and previous ischemic lesions, more in patients with IC-LAA." @default.
• W2071639384 created "2016-06-24" @default.
• W2071639384 creator A5024215409 @default.
• W2071639384 creator A5086195230 @default.
• W2071639384 date "2008-03-01" @default.
• W2071639384 modified "2023-09-27" @default.
• W2071639384 title "Association between metabolic syndrome and previous ischemic lesions in patients with intracranial atherosclerotic stroke" @default.
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• W2071639384 doi "https://doi.org/10.1016/j.clineuro.2007.10.016" @default.
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