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W2071639789 endingPage "458" @default.
W2071639789 startingPage "448" @default.
W2071639789 abstract "In response to various stresses, p53 is rapidly activated and transcriptionally regulates a number of target genes by which p53 modulates a variety of cellular activities. The transcriptional activity of p53 is delicately regulated by a plethora of cellular factors, independently or synergistically, in multiple ways in order to achieve a specific response. This article reviewed the role of the basal transcriptional machinery, co-activators, and co-repressors involved in p53-dependent transcription, and the underlying mechanism by which the p53 transcriptional activity is regulated. We also discussed some potentially interesting questions and future directions in the field." @default.
W2071639789 created "2016-06-24" @default.
W2071639789 creator A5002191937 @default.
W2071639789 creator A5028568020 @default.
W2071639789 date "2005-11-15" @default.
W2071639789 modified "2023-10-10" @default.
W2071639789 title "Regulation of the p53 transcriptional activity" @default.
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