FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071694471> ?p ?o ?g. }

• W2071694471 endingPage "380" @default.
• W2071694471 startingPage "369" @default.
• W2071694471 abstract "Enterohemorrhagic Escherichia coli O157:H7 (EHEC O157) is an important cause of food and waterborne illness in the developed countries. Cattle are a reservoir host of EHEC O157 and a major source of human exposure through contaminated meat products. Shiga toxins (Stxs) are an important pathogenicity trait of EHEC O157. The insertion sites of the Stx-encoding bacteriophages differentiate EHEC O157 isolates into genogroups commonly isolated from cattle but rarely from sick humans (bovine-biased genotypes [BBG]) and those commonly isolated from both cattle and human patients (clinical genotypes [CG]). Since BBG and CG share the cardinal virulence factors of EHEC O157 and are carried by cattle at similar prevalences, the infrequent occurrence of BBG among human disease isolates suggests that they may be less virulent than CG. We compared the virulence potentials of human and bovine isolates of CG and BBG in newborn conventional pig and weaned Dutch Belted rabbit models. CG-challenged piglets experienced severe disease accompanied by early and high mortality compared to BBG-challenged piglets. Similarly, CG-challenged rabbits were likely to develop lesions in kidney and intestine compared with the BBG-challenged rabbits. The CG strains used in this study carried stx2 and produced significantly higher amounts of Stx, whereas the BBG strains carried the stx2c gene variant only. These results suggest that BBG are less virulent than CG and that this difference in virulence potential is associated with the Stx2 subtype(s) carried and/or the amount of Stx produced." @default.
• W2071694471 created "2016-06-24" @default.
• W2071694471 creator A5003260011 @default.
• W2071694471 creator A5004199630 @default.
• W2071694471 creator A5004614024 @default.
• W2071694471 creator A5013541193 @default.
• W2071694471 creator A5020276351 @default.
• W2071694471 creator A5024428264 @default.
• W2071694471 creator A5036910312 @default.
• W2071694471 creator A5052744787 @default.
• W2071694471 creator A5058026752 @default.
• W2071694471 creator A5085802392 @default.
• W2071694471 date "2012-01-01" @default.
• W2071694471 modified "2023-10-18" @default.
• W2071694471 title "Differential Virulence of Clinical and Bovine-Biased Enterohemorrhagic Escherichia coli O157:H7 Genotypes in Piglet and Dutch Belted Rabbit Models" @default.
• W2071694471 cites W1904815041 @default.
• W2071694471 cites W1946414642 @default.
• W2071694471 cites W1955612312 @default.
• W2071694471 cites W1968294861 @default.
• W2071694471 cites W1984326040 @default.
• W2071694471 cites W1990386240 @default.
• W2071694471 cites W1996446565 @default.
• W2071694471 cites W2006076492 @default.
• W2071694471 cites W2008931521 @default.
• W2071694471 cites W2009338783 @default.
• W2071694471 cites W2013585313 @default.
• W2071694471 cites W2018146727 @default.
• W2071694471 cites W2025552324 @default.
• W2071694471 cites W2027435986 @default.
• W2071694471 cites W2033804375 @default.
• W2071694471 cites W2039987645 @default.
• W2071694471 cites W2045765967 @default.
• W2071694471 cites W2045859312 @default.
• W2071694471 cites W2046138148 @default.
• W2071694471 cites W2063629053 @default.
• W2071694471 cites W2075841017 @default.
• W2071694471 cites W2080708299 @default.
• W2071694471 cites W2080945212 @default.
• W2071694471 cites W2084295384 @default.
• W2071694471 cites W2091708538 @default.
• W2071694471 cites W2092376340 @default.
• W2071694471 cites W2094229855 @default.
• W2071694471 cites W2096516464 @default.
• W2071694471 cites W2099836442 @default.
• W2071694471 cites W2103798600 @default.
• W2071694471 cites W2103852158 @default.
• W2071694471 cites W2107188563 @default.
• W2071694471 cites W2108224099 @default.
• W2071694471 cites W2110739830 @default.
• W2071694471 cites W2114738492 @default.
• W2071694471 cites W2115182402 @default.
• W2071694471 cites W2118512642 @default.
• W2071694471 cites W2121713277 @default.
• W2071694471 cites W2122158907 @default.
• W2071694471 cites W2123994723 @default.
• W2071694471 cites W2124087841 @default.
• W2071694471 cites W2126969790 @default.
• W2071694471 cites W2127912613 @default.
• W2071694471 cites W2128591134 @default.
• W2071694471 cites W2131242123 @default.
• W2071694471 cites W2132032409 @default.
• W2071694471 cites W2135570736 @default.
• W2071694471 cites W2135648151 @default.
• W2071694471 cites W2139999454 @default.
• W2071694471 cites W2142657063 @default.
• W2071694471 cites W2143327879 @default.
• W2071694471 cites W2144222558 @default.
• W2071694471 cites W2144963709 @default.
• W2071694471 cites W2145857238 @default.
• W2071694471 cites W2147717655 @default.
• W2071694471 cites W2148262058 @default.
• W2071694471 cites W2149459245 @default.
• W2071694471 cites W2149572296 @default.
• W2071694471 cites W2149830825 @default.
• W2071694471 cites W2150086003 @default.
• W2071694471 cites W2152261560 @default.
• W2071694471 cites W2152964535 @default.
• W2071694471 cites W2154870173 @default.
• W2071694471 cites W2160403140 @default.
• W2071694471 cites W2162935803 @default.
• W2071694471 cites W2165369540 @default.
• W2071694471 cites W2167033798 @default.
• W2071694471 cites W2764803392 @default.
• W2071694471 doi "https://doi.org/10.1128/iai.05470-11" @default.
• W2071694471 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3255674" @default.
• W2071694471 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22025512" @default.
• W2071694471 hasPublicationYear "2012" @default.
• W2071694471 type Work @default.
• W2071694471 sameAs 2071694471 @default.
• W2071694471 citedByCount "34" @default.
• W2071694471 countsByYear W20716944712012 @default.
• W2071694471 countsByYear W20716944712013 @default.
• W2071694471 countsByYear W20716944712014 @default.
• W2071694471 countsByYear W20716944712015 @default.
• W2071694471 countsByYear W20716944712016 @default.
• W2071694471 countsByYear W20716944712017 @default.
• W2071694471 countsByYear W20716944712019 @default.
• W2071694471 countsByYear W20716944712020 @default.

• next