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- W2071708944 abstract "Abstract. Serum β2-microglobulin (S-β2m) was determined before treatment in fifty patients with multiple myeloma (MM), twenty-two of which had pure Bence Jones (BJ) myeloma. S-β2m was related to clinical stage before, but not after, a correction of S-β2m values for co-existent raised S-creatinine values (> 106 μmol 1-1)- However, S-β2m as well as corrected β2m was a parameter of prognostic value. The median expected survival time was 14 months at S-β2m values > 8·0 mg 1-1 and 56 months at values<3·5 mg 1-1. A response to treatment was associated with a decrease of S-β2m and a stationary course with unchanged values, whereas a relapse or progressive disease was connected with an increase. In β2m producers', i.e. patients with a clear initial high S-β2m, serial determinations are of value for monitoring patients with MM. In particular, this is the case in BJ myelomas, as they lack a quantifiable serum M-component. With respect to β2m no difference was found between BJ and other patients with MM." @default.
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- W2071708944 date "1985-10-01" @default.
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- W2071708944 title "Serum β2-microglobulin at remission and relapse in patients with multiple myeloma" @default.
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- W2071708944 doi "https://doi.org/10.1111/j.1365-2362.1985.tb00177.x" @default.
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