Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071716098> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2071716098 abstract "Purpose: Treatment planning for whole brain radiation treatment is technically a simple process but in practice it takes valuable clinical time of repetitive and tedious tasks. This report presents a method that automatically segments the relevant target and normal tissues and creates a treatment plan in only a few minutes after patient simulation. Methods: Segmentation is performed automatically through morphological operations on the soft tissue. The treatment plan is generated by searching a database of previous cases for patients with similar anatomy. In this search, each database case is ranked in terms of similarity using a customized metric designed for sensitivity by including only geometrical changes that affect the dose distribution. The database case with the best match is automatically modified to replace relevant patient info and isocenter position while maintaining original beam and MLC settings. Results: Fifteen patients were used to validate the method. In each of these cases the anatomy was accurately segmented to mean Dice coefficients of 0.970 ± 0.008 for the brain, 0.846 ± 0.009 for the eyes and 0.672 ± 0.111 for the lens as compared to clinical segmentations. Each case was then subsequently matched against a database of 70 validated treatment plans and themore » best matching plan (termed auto-planned), was compared retrospectively with the clinical plans in terms of brain coverage and maximum doses to critical structures. Maximum doses were reduced by a maximum of 20.809 Gy for the left eye (mean 3.533), by 13.352 (1.311) for the right eye, and by 27.471 (4.856), 25.218 (6.315) for the left and right lens. Time from simulation to auto-plan was 3-4 minutes. Conclusion: Automated database- based matching is an alternative to classical treatment planning that improves quality while providing a cost—effective solution to planning through modifying previous validated plans to match a current patient's anatomy.« less" @default.
- W2071716098 created "2016-06-24" @default.
- W2071716098 creator A5016594403 @default.
- W2071716098 creator A5019454697 @default.
- W2071716098 creator A5023012020 @default.
- W2071716098 creator A5029262430 @default.
- W2071716098 date "2014-05-29" @default.
- W2071716098 modified "2023-09-27" @default.
- W2071716098 title "SU-D-BRD-06: Automated Population-Based Planning for Whole Brain Radiation Therapy" @default.
- W2071716098 doi "https://doi.org/10.1118/1.4887885" @default.
- W2071716098 hasPublicationYear "2014" @default.
- W2071716098 type Work @default.
- W2071716098 sameAs 2071716098 @default.
- W2071716098 citedByCount "0" @default.
- W2071716098 crossrefType "journal-article" @default.
- W2071716098 hasAuthorship W2071716098A5016594403 @default.
- W2071716098 hasAuthorship W2071716098A5019454697 @default.
- W2071716098 hasAuthorship W2071716098A5023012020 @default.
- W2071716098 hasAuthorship W2071716098A5029262430 @default.
- W2071716098 hasConcept C103278499 @default.
- W2071716098 hasConcept C115961682 @default.
- W2071716098 hasConcept C126838900 @default.
- W2071716098 hasConcept C142724271 @default.
- W2071716098 hasConcept C153180895 @default.
- W2071716098 hasConcept C154945302 @default.
- W2071716098 hasConcept C162324750 @default.
- W2071716098 hasConcept C165064840 @default.
- W2071716098 hasConcept C176217482 @default.
- W2071716098 hasConcept C181401712 @default.
- W2071716098 hasConcept C19527891 @default.
- W2071716098 hasConcept C201645570 @default.
- W2071716098 hasConcept C21547014 @default.
- W2071716098 hasConcept C2908647359 @default.
- W2071716098 hasConcept C2989005 @default.
- W2071716098 hasConcept C31601959 @default.
- W2071716098 hasConcept C41008148 @default.
- W2071716098 hasConcept C509974204 @default.
- W2071716098 hasConcept C71924100 @default.
- W2071716098 hasConcept C89600930 @default.
- W2071716098 hasConcept C99454951 @default.
- W2071716098 hasConceptScore W2071716098C103278499 @default.
- W2071716098 hasConceptScore W2071716098C115961682 @default.
- W2071716098 hasConceptScore W2071716098C126838900 @default.
- W2071716098 hasConceptScore W2071716098C142724271 @default.
- W2071716098 hasConceptScore W2071716098C153180895 @default.
- W2071716098 hasConceptScore W2071716098C154945302 @default.
- W2071716098 hasConceptScore W2071716098C162324750 @default.
- W2071716098 hasConceptScore W2071716098C165064840 @default.
- W2071716098 hasConceptScore W2071716098C176217482 @default.
- W2071716098 hasConceptScore W2071716098C181401712 @default.
- W2071716098 hasConceptScore W2071716098C19527891 @default.
- W2071716098 hasConceptScore W2071716098C201645570 @default.
- W2071716098 hasConceptScore W2071716098C21547014 @default.
- W2071716098 hasConceptScore W2071716098C2908647359 @default.
- W2071716098 hasConceptScore W2071716098C2989005 @default.
- W2071716098 hasConceptScore W2071716098C31601959 @default.
- W2071716098 hasConceptScore W2071716098C41008148 @default.
- W2071716098 hasConceptScore W2071716098C509974204 @default.
- W2071716098 hasConceptScore W2071716098C71924100 @default.
- W2071716098 hasConceptScore W2071716098C89600930 @default.
- W2071716098 hasConceptScore W2071716098C99454951 @default.
- W2071716098 hasLocation W20717160981 @default.
- W2071716098 hasOpenAccess W2071716098 @default.
- W2071716098 hasPrimaryLocation W20717160981 @default.
- W2071716098 hasRelatedWork W1878962871 @default.
- W2071716098 hasRelatedWork W1976748598 @default.
- W2071716098 hasRelatedWork W2000358508 @default.
- W2071716098 hasRelatedWork W2001301796 @default.
- W2071716098 hasRelatedWork W2020598707 @default.
- W2071716098 hasRelatedWork W2024787791 @default.
- W2071716098 hasRelatedWork W2051456337 @default.
- W2071716098 hasRelatedWork W2052696148 @default.
- W2071716098 hasRelatedWork W2071162111 @default.
- W2071716098 hasRelatedWork W2077584985 @default.
- W2071716098 hasRelatedWork W2110372505 @default.
- W2071716098 hasRelatedWork W2191599379 @default.
- W2071716098 hasRelatedWork W2246298096 @default.
- W2071716098 hasRelatedWork W2509949850 @default.
- W2071716098 hasRelatedWork W2793496405 @default.
- W2071716098 hasRelatedWork W2921732463 @default.
- W2071716098 hasRelatedWork W3004814522 @default.
- W2071716098 hasRelatedWork W3006479069 @default.
- W2071716098 hasRelatedWork W3132298685 @default.
- W2071716098 hasRelatedWork W3149841110 @default.
- W2071716098 isParatext "false" @default.
- W2071716098 isRetracted "false" @default.
- W2071716098 magId "2071716098" @default.
- W2071716098 workType "article" @default.