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• W2071725907 abstract "Complex amino acids with an α-acyloxycarbonyl functionality in the side chain are easily available through epoxide opening by chelated enolates and subsequent oxidation/Passerini reaction. This protocol works with both, aldehyde and ketone intermediates, as long as the ketones are activated by electron-withdrawing groups. In principle Ugi reactions are also possible, allowing the generation of diamino acid derivatives." @default.
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• W2071725907 date "2011-09-19" @default.
• W2071725907 modified "2023-09-30" @default.
• W2071725907 title "A straightforward approach towards combined α-amino and α-hydroxy acids based on Passerini reactions" @default.
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• W2071725907 doi "https://doi.org/10.3762/bjoc.7.151" @default.
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