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• W2071726812 abstract "Despite memory failures being a central feature of amnestic mild cognitive impairment (a-MCI), there is limited research into the nature of the memory impairment associated with this condition. A further understanding could lead to refinement of criteria needed to qualify for this designation and aid in prediction of who will progress to development of clinical Alzheimer's disease. Dual process models posit that recognition memory is supported by the dissociable processes of recollection and familiarity. The present study sought to evaluate recognition memory in a-MCI in the framework of the dual process model. Patients with a-MCI and age- and education-matched controls were tested on three memory paradigms. Two paradigms were modifications of the process-dissociation procedure in which recollection required either memory of word-pair associations (associative) or the font color of words at study (featural). A final paradigm utilized the task-dissociation methodology comparing performance for item and visual spatial source memory. All three tasks revealed that familiarity was impaired to at least the same extent as recollection. As familiarity is thought to be spared in normal aging, its measurement may provide a relatively specific marker for the early pathological changes of Alzheimer's disease." @default.
• W2071726812 created "2016-06-24" @default.
• W2071726812 creator A5036815556 @default.
• W2071726812 creator A5041387594 @default.
• W2071726812 creator A5089868309 @default.
• W2071726812 date "2008-06-01" @default.
• W2071726812 modified "2023-10-13" @default.
• W2071726812 title "Recollection and familiarity in amnestic mild cognitive impairment: A global decline in recognition memory" @default.
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• W2071726812 doi "https://doi.org/10.1016/j.neuropsychologia.2008.01.017" @default.
• W2071726812 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2519866" @default.
• W2071726812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18328509" @default.
• W2071726812 hasPublicationYear "2008" @default.
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