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- W2071738118 abstract "B cell development is a multistep process that is tightly regulated at the transcriptional level. In recent years, investigators have shed light on the transcription factor networks involved in all the differentiation steps comprising B lymphopoiesis. The interplay between transcription factors and the epigenetic machinery involved in establishing the correct genomic landscape characteristic of each cellular state is beginning to be dissected. The participation of “epigenetic regulator-transcription factor” complexes is also crucial for directing cells during reprogramming into pluripotency or lineage conversion. In this context, greater knowledge of epigenetic regulation during B cell development, transdifferentiation, and reprogramming will enable us to understand better how epigenetics can control cell lineage commitment and identity. Herein, we review the current knowledge about the epigenetic events that contribute to B cell development and reprogramming." @default.
- W2071738118 created "2016-06-24" @default.
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- W2071738118 creator A5069989737 @default.
- W2071738118 creator A5077282469 @default.
- W2071738118 creator A5081765866 @default.
- W2071738118 date "2012-01-01" @default.
- W2071738118 modified "2023-10-16" @default.
- W2071738118 title "Epigenetic Regulation of B Lymphocyte Differentiation, Transdifferentiation, and Reprogramming" @default.
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- W2071738118 doi "https://doi.org/10.1155/2012/564381" @default.
- W2071738118 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3444840" @default.
- W2071738118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22997486" @default.
- W2071738118 hasPublicationYear "2012" @default.