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- W2071750956 abstract "For the individual molecules in a particular sample of calf thymus DNA, we find: The Eigner-Doty relation between viscosity and sedimentation coefficients is reasonably well obeyed below 25 s. Therefore, the polydispersity in sedimentation coefficient for these macromolecules is largely or entirely due to a polydispersity in molecular weights. Above 25 s for this sample of calf thymus DNA, the observed viscosities fall below those which would be predicted by the Eigner-Doty curve. Above 42 s, the viscosity actually declines with increasing sedimentation coefficient. The probable explanation for these observations is that there is a change in shape of the more rapidly sedimenting DNA molecules, caused either by denaturation or by protein cross-linkages. We favor the latter possibility." @default.
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- W2071750956 date "1965-07-01" @default.
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- W2071750956 title "An analysis of the sedimentation coefficient distribution of a sample of calf thymus DNA" @default.
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- W2071750956 doi "https://doi.org/10.1016/s0022-2836(65)80309-6" @default.
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