Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071751775> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2071751775 endingPage "734" @default.
- W2071751775 startingPage "732" @default.
- W2071751775 abstract "Recurrent bacterial vaginosis (RBV) is extremely common and a source of frustration to patient and practitioners alike. In the absence of curative therapy, practitioners resort to retreating each individual episode. It has been suggested that vaginal biofilm in BV facilitates persistence of bacterial pathogens. Accordingly, topical boric acid (BA) aimed at biofilm removal was added to nitroimidazole induction and maintenance therapy creating a triple phase regimen to reduce symptomatic recurrence of BV in high-risk patients.Uncontrolled, nonrandomized, retrospective chart review of patients with RBV treated with 7 days of oral nitroimidazole; followed by 21 days of intravaginal BA 600 mg/day and if in remission treated with metronidazole gel twice weekly for 16 weeks. Outcome was determined using Amsel criteria.Fifty-eight women were treated for a total of 77 episodes of RBV. Sixty episodes of BV were available for a follow-up evaluation 4 to 12 weeks after enrollment, having completed both nitroimidazole and BA therapy and before initiating vaginal metronidazole gel. Cure after nitroimidazole and BA therapy ranged from 88% to 92%, 7 and 12 weeks after the initial visit, respectively. Cumulative cure at 12, 16, and 28 weeks from initial visit was 87%, 78%, and 65%, respectively. A failure rate of 50% was documented by 36 weeks of follow-up. No adverse effects of BA were observed.Clinical experience with a triple phase maintenance regimen for women with RBV was encouraging but requires validation in a prospective randomized controlled study." @default.
- W2071751775 created "2016-06-24" @default.
- W2071751775 creator A5000393916 @default.
- W2071751775 creator A5054286469 @default.
- W2071751775 creator A5070668494 @default.
- W2071751775 date "2009-11-01" @default.
- W2071751775 modified "2023-10-16" @default.
- W2071751775 title "Boric Acid Addition to Suppressive Antimicrobial Therapy for Recurrent Bacterial Vaginosis" @default.
- W2071751775 cites W1511490662 @default.
- W2071751775 cites W1983918621 @default.
- W2071751775 cites W2031894451 @default.
- W2071751775 cites W2058566083 @default.
- W2071751775 cites W2061198932 @default.
- W2071751775 cites W2069094871 @default.
- W2071751775 cites W2072409597 @default.
- W2071751775 cites W2077338243 @default.
- W2071751775 cites W2086129721 @default.
- W2071751775 cites W2108487398 @default.
- W2071751775 cites W2113857827 @default.
- W2071751775 cites W2155483929 @default.
- W2071751775 doi "https://doi.org/10.1097/olq.0b013e3181b08456" @default.
- W2071751775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19704395" @default.
- W2071751775 hasPublicationYear "2009" @default.
- W2071751775 type Work @default.
- W2071751775 sameAs 2071751775 @default.
- W2071751775 citedByCount "87" @default.
- W2071751775 countsByYear W20717517752012 @default.
- W2071751775 countsByYear W20717517752013 @default.
- W2071751775 countsByYear W20717517752014 @default.
- W2071751775 countsByYear W20717517752015 @default.
- W2071751775 countsByYear W20717517752016 @default.
- W2071751775 countsByYear W20717517752017 @default.
- W2071751775 countsByYear W20717517752018 @default.
- W2071751775 countsByYear W20717517752019 @default.
- W2071751775 countsByYear W20717517752020 @default.
- W2071751775 countsByYear W20717517752021 @default.
- W2071751775 countsByYear W20717517752022 @default.
- W2071751775 countsByYear W20717517752023 @default.
- W2071751775 crossrefType "journal-article" @default.
- W2071751775 hasAuthorship W2071751775A5000393916 @default.
- W2071751775 hasAuthorship W2071751775A5054286469 @default.
- W2071751775 hasAuthorship W2071751775A5070668494 @default.
- W2071751775 hasBestOaLocation W20717517751 @default.
- W2071751775 hasConcept C126322002 @default.
- W2071751775 hasConcept C141071460 @default.
- W2071751775 hasConcept C197934379 @default.
- W2071751775 hasConcept C2777396551 @default.
- W2071751775 hasConcept C2779952448 @default.
- W2071751775 hasConcept C2781413609 @default.
- W2071751775 hasConcept C29456083 @default.
- W2071751775 hasConcept C501593827 @default.
- W2071751775 hasConcept C71924100 @default.
- W2071751775 hasConcept C86803240 @default.
- W2071751775 hasConcept C89423630 @default.
- W2071751775 hasConcept C90924648 @default.
- W2071751775 hasConceptScore W2071751775C126322002 @default.
- W2071751775 hasConceptScore W2071751775C141071460 @default.
- W2071751775 hasConceptScore W2071751775C197934379 @default.
- W2071751775 hasConceptScore W2071751775C2777396551 @default.
- W2071751775 hasConceptScore W2071751775C2779952448 @default.
- W2071751775 hasConceptScore W2071751775C2781413609 @default.
- W2071751775 hasConceptScore W2071751775C29456083 @default.
- W2071751775 hasConceptScore W2071751775C501593827 @default.
- W2071751775 hasConceptScore W2071751775C71924100 @default.
- W2071751775 hasConceptScore W2071751775C86803240 @default.
- W2071751775 hasConceptScore W2071751775C89423630 @default.
- W2071751775 hasConceptScore W2071751775C90924648 @default.
- W2071751775 hasIssue "11" @default.
- W2071751775 hasLocation W20717517751 @default.
- W2071751775 hasLocation W20717517752 @default.
- W2071751775 hasLocation W20717517753 @default.
- W2071751775 hasOpenAccess W2071751775 @default.
- W2071751775 hasPrimaryLocation W20717517751 @default.
- W2071751775 hasRelatedWork W1993536251 @default.
- W2071751775 hasRelatedWork W2031158406 @default.
- W2071751775 hasRelatedWork W2068637245 @default.
- W2071751775 hasRelatedWork W2071751775 @default.
- W2071751775 hasRelatedWork W2085496549 @default.
- W2071751775 hasRelatedWork W2143468386 @default.
- W2071751775 hasRelatedWork W2170891532 @default.
- W2071751775 hasRelatedWork W2380001549 @default.
- W2071751775 hasRelatedWork W3149366556 @default.
- W2071751775 hasRelatedWork W68766335 @default.
- W2071751775 hasVolume "36" @default.
- W2071751775 isParatext "false" @default.
- W2071751775 isRetracted "false" @default.
- W2071751775 magId "2071751775" @default.
- W2071751775 workType "article" @default.