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- W2071780639 endingPage "620" @default.
- W2071780639 startingPage "614" @default.
- W2071780639 abstract "Mammalian neurons can synthesize choline by methylating phosphatidylethanolamine and hydrolyzing the resulting phosphatidylcholine. This process is stimulated by catecholamines. The phosphatidylethanolamine is synthesized in part from phosphatidylserine; hence the amino acids methionine (acting after conversion to S-adenosylmethionine) and serine can be the ultimate precursors of choline. Brain choline concentrations are generally higher than plasma concentrations, but depend on plasma concentrations because of the kinetic characteristics of the blood-brain-barrier transport system. When cholinergic neurons are activated, acetylcholine release can be enhanced by treatments that increase plasma choline (for example, consumption of certain foods)." @default.
- W2071780639 created "2016-06-24" @default.
- W2071780639 creator A5016465475 @default.
- W2071780639 creator A5086674512 @default.
- W2071780639 date "1983-08-12" @default.
- W2071780639 modified "2023-10-18" @default.
- W2071780639 title "Choline and Cholinergic Neurons" @default.
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