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- W2071799520 abstract "A study of the toxicity of INH given at high dosage and simultaneously administered with glutamic acid has been carried out. Fourteen patients with chronic far advanced pulmonary tuberculosis, previously treated with antibiotics at standard doses, were treated with INH at daily doses of 20 milligrams per kilogram of body weight. Nine of them received INH without glutamic acid and served as a control group. Five others, plus five others later added from the control group, were treated with INH at 20 milligrams per kilogram together with glutamic acid, at a rate of 10 milligrams per each milligram of INH. All the patients received 100 milligrams of pyridoxine daily. Liver function tests as well as serial EEG tracings were performed. Glutamic acid lessens notably the toxicity due to INH. It is of great interest that use of glutamic acid remarkably improved patient appetite, weight gain, and feeling of well-being." @default.
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- W2071799520 date "1960-04-01" @default.
- W2071799520 modified "2023-09-27" @default.
- W2071799520 title "Pulmonary Tuberculosis Treated with High Doses of INH plus Glutamic Acid" @default.
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- W2071799520 doi "https://doi.org/10.1378/chest.37.4.382" @default.
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