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- W2071801269 abstract "Fluorescence in situ hybridization (FISH) with a combination of three composite whole chromosome-specific DNA probes for human chromosomes 1, 4 and 12 was used to analyse in vitro radiation-induced dicentrics and symmetrical translocations in peripheral lymphocytes. Translocations could be rapidly and efficiently detected by FISH. Their frequencies were 1.8-fold higher than the frequencies for dicentrics at a given dose. The dose-response curves for translocations and dicentrics were linear quadratic with a significant higher quadratic component for translocations. The application of FISH for scoring stable translocations for biological dosimetry of radiation exposures is discussed." @default.
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- W2071801269 date "1992-01-01" @default.
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- W2071801269 title "Radiation-induced Chromosome Aberrations Analysed by Fluorescence<i>in Situ</i>Hybridization with a Triple Combination of Composite Whole Chromosome-specific DNA Probes" @default.
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- W2071801269 doi "https://doi.org/10.1080/09553009214552621" @default.
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