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- W2071801650 endingPage "522" @default.
- W2071801650 startingPage "509" @default.
- W2071801650 abstract "Rabeprazole is a proton pump inhibitor (PPI) presenting a very advantageous pharmacodynamic and pharmacokinetic profile over older PPIs. In particular, this drug has a very fast onset of action, due to a short activation time and a very high pKa, and may therefore be defined as a ‘second generation’ PPI. The aim of this article is to provide an update on the pharmacology and clinical profile of rabeprazole and its use in acid-related disorders, with a particular focus on its role in gastroesophageal reflux disease; in the treatment and prevention of duodenal and gastric ulcers and Zollinger–Ellison syndrome; in the therapy of the extraesophageal manifestations of gastroesophageal reflux disease (in particular the respiratory and ear, nose and throat ones); and in the eradication of Helicobacter pylori." @default.
- W2071801650 created "2016-06-24" @default.
- W2071801650 creator A5031330585 @default.
- W2071801650 creator A5045353132 @default.
- W2071801650 creator A5047413454 @default.
- W2071801650 date "2008-08-01" @default.
- W2071801650 modified "2023-10-18" @default.
- W2071801650 title "Rabeprazole: a second-generation proton pump inhibitor in the treatment of acid-related disease" @default.
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- W2071801650 doi "https://doi.org/10.1586/17474124.2.4.509" @default.
- W2071801650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19072398" @default.
- W2071801650 hasPublicationYear "2008" @default.
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