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- W2071807335 abstract "Amphoteric calix[8]arene with negatively charged upper rim and positively charged lower rim was synthesized based on water-soluble p-sulfonato-calix[8]arene. The pH-sensitive amphoteric calix[8]arenes exhibit not only a good hydrophobic drug loading capacity but also a pH-triggered drug releasing behavior. The in vitro release studies demonstrated that release of ciprofloxacin from amphoteric calix[8]arene complexes was highly pH-sensitive. More efficient drug release was observed at mildly acidic pH 5.0 and basic pH 8.5 compared to physiological pH. The amphoteric calix[8]arene complexes hold out great promise of being pH-sensitive drug carrier." @default.
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- W2071807335 date "2013-01-01" @default.
- W2071807335 modified "2023-09-25" @default.
- W2071807335 title "Amphoteric calix[8]arene-based complex for pH-triggered drug delivery" @default.
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- W2071807335 doi "https://doi.org/10.1016/j.colsurfb.2012.06.022" @default.
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