FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2071837997> ?p ?o ?g. }

• W2071837997 endingPage "503" @default.
• W2071837997 startingPage "496" @default.
• W2071837997 abstract "Controlled release studies of DNA from polymers have been limited, with most studies concentrating on microsphere formulations. This report details a study done on the release and transfection efficiencies of pDNA-lipofectamine complex (lipoplex), from selected polymeric films in which it was dispersed; the release and transfection efficiency was compared with that of naked pDNA. A biodegradable and a biostable polymer were compared. A sustained release profile was obtained from both the polymeric films. For the release of pDNA (naked DNA), a burst effect was always seen, and was suppressed using additives; for complexed pDNA (lipoplex), the release was slow, but could be accelerated using additives. The compositions of the released lipoplexes were also quantified in terms of the fraction that was complexed. In addition, the transfection efficiency of the released complexes and of the naked pDNA was determined in vitro using COS 7 cells. The results also demonstrated that bioactivity of the released complexed pDNA was superior to that of the released naked DNA. Such formulations may be useful for local sustained delivery of lipoplexes from implanted films. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2008" @default.
• W2071837997 created "2016-06-24" @default.
• W2071837997 creator A5004556300 @default.
• W2071837997 creator A5018350409 @default.
• W2071837997 creator A5043812397 @default.
• W2071837997 creator A5044423177 @default.
• W2071837997 date "2008-01-01" @default.
• W2071837997 modified "2023-09-26" @default.
• W2071837997 title "Sustained release of complexed and naked DNA from polymer films" @default.
• W2071837997 cites W1506102129 @default.
• W2071837997 cites W1981508315 @default.
• W2071837997 cites W2010818956 @default.
• W2071837997 cites W2034269897 @default.
• W2071837997 cites W2045321923 @default.
• W2071837997 cites W2048600393 @default.
• W2071837997 cites W2048849036 @default.
• W2071837997 cites W2055092476 @default.
• W2071837997 cites W2071103044 @default.
• W2071837997 cites W2079837293 @default.
• W2071837997 cites W2090030769 @default.
• W2071837997 cites W2114567767 @default.
• W2071837997 cites W2117372374 @default.
• W2071837997 cites W2135622769 @default.
• W2071837997 cites W2163448064 @default.
• W2071837997 doi "https://doi.org/10.1002/jbm.b.30971" @default.
• W2071837997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18076090" @default.
• W2071837997 hasPublicationYear "2008" @default.
• W2071837997 type Work @default.
• W2071837997 sameAs 2071837997 @default.
• W2071837997 citedByCount "15" @default.
• W2071837997 countsByYear W20718379972013 @default.
• W2071837997 countsByYear W20718379972016 @default.
• W2071837997 countsByYear W20718379972017 @default.
• W2071837997 countsByYear W20718379972018 @default.
• W2071837997 countsByYear W20718379972019 @default.
• W2071837997 crossrefType "journal-article" @default.
• W2071837997 hasAuthorship W2071837997A5004556300 @default.
• W2071837997 hasAuthorship W2071837997A5018350409 @default.
• W2071837997 hasAuthorship W2071837997A5043812397 @default.
• W2071837997 hasAuthorship W2071837997A5044423177 @default.
• W2071837997 hasConcept C104317684 @default.
• W2071837997 hasConcept C12554922 @default.
• W2071837997 hasConcept C127413603 @default.
• W2071837997 hasConcept C135983454 @default.
• W2071837997 hasConcept C159985019 @default.
• W2071837997 hasConcept C171250308 @default.
• W2071837997 hasConcept C185592680 @default.
• W2071837997 hasConcept C188027245 @default.
• W2071837997 hasConcept C192562407 @default.
• W2071837997 hasConcept C195856716 @default.
• W2071837997 hasConcept C40767141 @default.
• W2071837997 hasConcept C42360764 @default.
• W2071837997 hasConcept C49923114 @default.
• W2071837997 hasConcept C521977710 @default.
• W2071837997 hasConcept C54009773 @default.
• W2071837997 hasConcept C54355233 @default.
• W2071837997 hasConcept C552990157 @default.
• W2071837997 hasConcept C55493867 @default.
• W2071837997 hasConcept C81885089 @default.
• W2071837997 hasConcept C86803240 @default.
• W2071837997 hasConcept C92087593 @default.
• W2071837997 hasConceptScore W2071837997C104317684 @default.
• W2071837997 hasConceptScore W2071837997C12554922 @default.
• W2071837997 hasConceptScore W2071837997C127413603 @default.
• W2071837997 hasConceptScore W2071837997C135983454 @default.
• W2071837997 hasConceptScore W2071837997C159985019 @default.
• W2071837997 hasConceptScore W2071837997C171250308 @default.
• W2071837997 hasConceptScore W2071837997C185592680 @default.
• W2071837997 hasConceptScore W2071837997C188027245 @default.
• W2071837997 hasConceptScore W2071837997C192562407 @default.
• W2071837997 hasConceptScore W2071837997C195856716 @default.
• W2071837997 hasConceptScore W2071837997C40767141 @default.
• W2071837997 hasConceptScore W2071837997C42360764 @default.
• W2071837997 hasConceptScore W2071837997C49923114 @default.
• W2071837997 hasConceptScore W2071837997C521977710 @default.
• W2071837997 hasConceptScore W2071837997C54009773 @default.
• W2071837997 hasConceptScore W2071837997C54355233 @default.
• W2071837997 hasConceptScore W2071837997C552990157 @default.
• W2071837997 hasConceptScore W2071837997C55493867 @default.
• W2071837997 hasConceptScore W2071837997C81885089 @default.
• W2071837997 hasConceptScore W2071837997C86803240 @default.
• W2071837997 hasConceptScore W2071837997C92087593 @default.
• W2071837997 hasIssue "2" @default.
• W2071837997 hasLocation W20718379971 @default.
• W2071837997 hasLocation W20718379972 @default.
• W2071837997 hasOpenAccess W2071837997 @default.
• W2071837997 hasPrimaryLocation W20718379971 @default.
• W2071837997 hasRelatedWork W1970092772 @default.
• W2071837997 hasRelatedWork W1975032155 @default.
• W2071837997 hasRelatedWork W1992909684 @default.
• W2071837997 hasRelatedWork W2025536407 @default.
• W2071837997 hasRelatedWork W2071837997 @default.
• W2071837997 hasRelatedWork W2089633391 @default.
• W2071837997 hasRelatedWork W2090699031 @default.
• W2071837997 hasRelatedWork W2093299893 @default.
• W2071837997 hasRelatedWork W2159486117 @default.
• W2071837997 hasRelatedWork W2747227528 @default.
• W2071837997 hasVolume "85B" @default.

• next