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- W2071846919 abstract "During our continuing study of pteridine metabolism, the need arose for a more rapid and quantitative determination of pterins in biological fluids. By adopting and modifying previously developed techniques, we have obtained a rapid and sensitive method that allows the simultaneous determination of eight different pterins in human urine and blood. When examined over a 10-day period, the levels of pterins excreted by a normal individual averaged the following values expressed in picomoles per mg of creatinine: biopterin, 9104; neopterin, 6018; xanthopterin, 6561; pterin, 1136; isoxanthopterin, 636; pterin-6-carboxylate, 483; and 6-hydroxymethylpterin, 315. Moreover, 6-hydroxymethylpterin and pterin-6-carboxaldehyde were detected for the first time in the blood of normal individuals." @default.
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- W2071846919 date "1980-02-01" @default.
- W2071846919 modified "2023-09-27" @default.
- W2071846919 title "Quantitative determination of pterins in biological fluids by high-performance liquid chromatography" @default.
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- W2071846919 doi "https://doi.org/10.1016/s0021-9673(00)81259-5" @default.
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