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- W2071893776 abstract "A 67-year-old white man with a 20-year history of hidradenitis suppurativa (HS) presented for treatment of painful purulent draining sinuses, cysts, and nodules involving his ears, axillae, buttocks, and groin. His medical history was notable for inflammatory bowel disease, which had been treated with a total colectomy in 1971. Prior treatments for his HS included multiple courses of oral antibiotics, surgical resection of the buttocks and axillae, and radiation therapy to his left ear in an attempt to improve the swelling and anatomical disfigurement that were impairing his auditory function. Cultures from his left ear were positive for Escherichia coli. At the time of referral, he was being treated with augmentin (875 mg twice a day) for his HS and associated left otitis externa, otitis media, and mastoiditis. This therapy yielded mild improvement, but the patient continued to have significant pain, drainage, and hearing impairment. Physical examination revealed a hypertrophic, edematous, erythematous left earlobe, with draining sinuses obstructing the external auditory canal and similar but less severe findings involving the right earlobe and retroauricular region. Both axillae were erythematous and tender, with purulent draining sinuses and hypertrophic scarring from past surgical excisions and inflammation. The groin showed erythema and multiple draining sinuses, with dissection of the right scrotum revealing visible connective tissue. The buttocks had 2 large surgical defects down to the level of the gluteal muscle, with perianal erythematous, purulent, draining fistulae." @default.
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- W2071893776 date "2006-09-01" @default.
- W2071893776 modified "2023-10-11" @default.
- W2071893776 title "Severe Hidradenitis Suppurativa Treated With Adalimumab" @default.
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- W2071893776 doi "https://doi.org/10.1001/archderm.142.9.1110" @default.
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