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- W2072001145 abstract "Oneofthetroubles ofusingtheendogenous creatinine clearance tomeasure thefiltration rate is that plasma andserumcontain chromogens, other thancreatinine, whichgiveacolour withtheJaffe reaction. Thecreatinine can,however, beisolated by adsorption on Fuller's earth(Gaebler and Keltch, 1928) andsubsequently eluted withthe alkaline picrate usedforcolourproduction (Borsook, 1935). Thismethodhasbeenusedbya numberofworkers anditsreliability established. ThusHareandHare(1949) foundwithradioactive carbonthatrecovery iscomplete, and Ralston (1955) withchromatography thatno extraneous chromogen remains aftertreatment. Butthere isverylittle evidence astotheamounts ofnon-creatinine chromogen intheplasma oras tohow neglect ofitspresence influences the creatinine clearance, anditisthese points which will beconsidered here." @default.
- W2072001145 created "2016-06-24" @default.
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- W2072001145 date "1958-03-01" @default.
- W2072001145 modified "2023-09-25" @default.
- W2072001145 title "Plasma Chromogen and the Endogenous Creatinine Clearance" @default.
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- W2072001145 doi "https://doi.org/10.1136/jcp.11.2.173" @default.
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