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- W2072012146 abstract "Abstract Enumeration and characterization of circulating tumor cells (CTCs) can provide information on patient prognosis and treatment efficacy. However, CTCs are rare, making their isolation a major technological challenge. We developed a technique for enrichment, and subsequent characterization of CTCs based on efficient depletion of human leukocytes. : The technique (CanPatrol The spiking experiments showed that the average efficacy of leukocytes depletion was 99.98% and the average tumor cells recovery was not lower than 80%. FISH could be used to perform The technique we developed allowed isolation and characterization of circulating epithelial tumor cells that do not express classical epithelial antigens. This potentially leads to a more accurate enumeration of the number of CTCs and is suitable for application to a broad range of cancers." @default.
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- W2072012146 date "2014-01-01" @default.
- W2072012146 modified "2023-09-27" @default.
- W2072012146 title "Enrichment and enumeration of circulating tumor cells by efficient depletion of leukocyte fractions" @default.
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- W2072012146 doi "https://doi.org/10.1515/cclm-2013-0558" @default.
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