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- W2072017376 abstract "The transcription termination site for yeast RNA polymerase I requires not only an 11 bp binding site for Reb1p, but also about 46 bp of 5′ flanking sequence. We propose that Reb1p bound to its site is part of a pause element, while the 5′ flanking sequence contains a release element. Pausing requires little other than the DNA-binding domain of Reb1p and is not specific for polymerase I. The release element, however, can be polymerase specific. We propose a general model for eukaryotic transcription terminators in which termination occurs when a relatively nonspecific signal induces polymerase to pause in the context of a release element." @default.
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- W2072017376 date "1994-11-01" @default.
- W2072017376 modified "2023-09-30" @default.
- W2072017376 title "A model for transcription termination by RNA polymerase I" @default.
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- W2072017376 doi "https://doi.org/10.1016/0092-8674(94)90261-5" @default.
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