Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072044572> ?p ?o ?g. }
- W2072044572 endingPage "972" @default.
- W2072044572 startingPage "964" @default.
- W2072044572 abstract "Abstract The aim of this study was to evaluate the osteogenic potential of embroidered, tissue‐engineered polycaprolactone‐ co ‐lactide (trade name: PCL) scaffolds for the reconstruction of large bone defects. Ten piled‐up PCL scaffolds were implanted in femura with a critical size defect of immunodeficient nude rats for 12 weeks [ n = 4, group 1: noncoated, group 2: collagen I (coll I), group 3: collagen I/chondroitin sulfate (coll I/CS), and group 4: collagen I/chondroitin sulfate/human mesenchymal stem cells (coll I/CS/hMSC)]. X‐ray examination, computer tomography, and histological analyses of the explanted scaffold pads were performed. The quantification of the bone volume ratio showed a significantly higher rate of new bone formation at coll I/CS‐coated scaffolds compared with the other groups. Histological investigations revealed that the defect reconstruction started from the peripheral bone ends and incorporated into the scaffold material. Additionally seeded hMSC on coll I/CS‐coated scaffolds showed a higher matrix deposition inside the implant but no higher bone formation was observed. These data imply that the coll I/CS‐coated PCL scaffolds have the highest potential for treating critical size defects. The scaffolds, being variable in size and structure, can be adapted to any bone defect. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010." @default.
- W2072044572 created "2016-06-24" @default.
- W2072044572 creator A5008314609 @default.
- W2072044572 creator A5024039575 @default.
- W2072044572 creator A5026604224 @default.
- W2072044572 creator A5038552816 @default.
- W2072044572 creator A5045665079 @default.
- W2072044572 creator A5053362531 @default.
- W2072044572 creator A5058292737 @default.
- W2072044572 creator A5077105423 @default.
- W2072044572 creator A5077928584 @default.
- W2072044572 date "2010-09-07" @default.
- W2072044572 modified "2023-10-18" @default.
- W2072044572 title "Long-bone critical-size defects treated with tissue-engineered polycaprolactone-co-lactide scaffolds: A pilot study on rats" @default.
- W2072044572 cites W1888248494 @default.
- W2072044572 cites W1969358976 @default.
- W2072044572 cites W1971113558 @default.
- W2072044572 cites W1971339046 @default.
- W2072044572 cites W1971931848 @default.
- W2072044572 cites W1992192460 @default.
- W2072044572 cites W2004851192 @default.
- W2072044572 cites W2021684526 @default.
- W2072044572 cites W2022050255 @default.
- W2072044572 cites W2026975571 @default.
- W2072044572 cites W2027868664 @default.
- W2072044572 cites W2028187667 @default.
- W2072044572 cites W2041960987 @default.
- W2072044572 cites W2051292479 @default.
- W2072044572 cites W2074727818 @default.
- W2072044572 cites W2077648724 @default.
- W2072044572 cites W2078951220 @default.
- W2072044572 cites W2080039066 @default.
- W2072044572 cites W2084304606 @default.
- W2072044572 cites W2089273654 @default.
- W2072044572 cites W2091548381 @default.
- W2072044572 cites W2103745164 @default.
- W2072044572 cites W2109293470 @default.
- W2072044572 cites W2109846255 @default.
- W2072044572 cites W2110307716 @default.
- W2072044572 cites W2139457077 @default.
- W2072044572 cites W2152297596 @default.
- W2072044572 cites W2153532237 @default.
- W2072044572 cites W2163109093 @default.
- W2072044572 cites W4240767188 @default.
- W2072044572 cites W429784392 @default.
- W2072044572 doi "https://doi.org/10.1002/jbm.a.32878" @default.
- W2072044572 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20824650" @default.
- W2072044572 hasPublicationYear "2010" @default.
- W2072044572 type Work @default.
- W2072044572 sameAs 2072044572 @default.
- W2072044572 citedByCount "28" @default.
- W2072044572 countsByYear W20720445722012 @default.
- W2072044572 countsByYear W20720445722013 @default.
- W2072044572 countsByYear W20720445722014 @default.
- W2072044572 countsByYear W20720445722015 @default.
- W2072044572 countsByYear W20720445722016 @default.
- W2072044572 countsByYear W20720445722017 @default.
- W2072044572 countsByYear W20720445722018 @default.
- W2072044572 countsByYear W20720445722019 @default.
- W2072044572 countsByYear W20720445722020 @default.
- W2072044572 countsByYear W20720445722022 @default.
- W2072044572 countsByYear W20720445722023 @default.
- W2072044572 crossrefType "journal-article" @default.
- W2072044572 hasAuthorship W2072044572A5008314609 @default.
- W2072044572 hasAuthorship W2072044572A5024039575 @default.
- W2072044572 hasAuthorship W2072044572A5026604224 @default.
- W2072044572 hasAuthorship W2072044572A5038552816 @default.
- W2072044572 hasAuthorship W2072044572A5045665079 @default.
- W2072044572 hasAuthorship W2072044572A5053362531 @default.
- W2072044572 hasAuthorship W2072044572A5058292737 @default.
- W2072044572 hasAuthorship W2072044572A5077105423 @default.
- W2072044572 hasAuthorship W2072044572A5077928584 @default.
- W2072044572 hasConcept C105702510 @default.
- W2072044572 hasConcept C136229726 @default.
- W2072044572 hasConcept C141071460 @default.
- W2072044572 hasConcept C142724271 @default.
- W2072044572 hasConcept C153074725 @default.
- W2072044572 hasConcept C159985019 @default.
- W2072044572 hasConcept C192562407 @default.
- W2072044572 hasConcept C198826908 @default.
- W2072044572 hasConcept C2779553658 @default.
- W2072044572 hasConcept C2779868350 @default.
- W2072044572 hasConcept C2781411149 @default.
- W2072044572 hasConcept C521977710 @default.
- W2072044572 hasConcept C71924100 @default.
- W2072044572 hasConcept C89429830 @default.
- W2072044572 hasConceptScore W2072044572C105702510 @default.
- W2072044572 hasConceptScore W2072044572C136229726 @default.
- W2072044572 hasConceptScore W2072044572C141071460 @default.
- W2072044572 hasConceptScore W2072044572C142724271 @default.
- W2072044572 hasConceptScore W2072044572C153074725 @default.
- W2072044572 hasConceptScore W2072044572C159985019 @default.
- W2072044572 hasConceptScore W2072044572C192562407 @default.
- W2072044572 hasConceptScore W2072044572C198826908 @default.
- W2072044572 hasConceptScore W2072044572C2779553658 @default.
- W2072044572 hasConceptScore W2072044572C2779868350 @default.
- W2072044572 hasConceptScore W2072044572C2781411149 @default.
- W2072044572 hasConceptScore W2072044572C521977710 @default.