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- W2072074580 abstract "The role of primordial yolk platelets (PYPs) in the transport of the yolk precursor vitellogenin to the yolk platelets in Xenopus laevis oocytes has been demonstrated by electron microscopic autoradiography. Within 20 min after exposure of the oocyte to 3H-labeled-vitellogenin, silver grains are associated with small PYPs which are formed by the fusion of endosomes. At 40 min after incorporation of 3H-labeled vitellogenin, autoradiographic silver grains are associated with larger PYPs and with the superficial layer of yolk platelets. Thus, the results demonstrate that PYPs are an intermediate in the transport of vitellogenin from endosomes to yolk platelets. These observations are consonant with the general hypothesis that vitellogenin first associates (binds?) with the plasma membrane, then is incorporated by endocytosis into endosomes which fuse to form PYPs, and finally the contents of the PYPs are eventually deposited into yolk platelets." @default.
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- W2072074580 date "1977-10-01" @default.
- W2072074580 modified "2023-10-03" @default.
- W2072074580 title "Intracellular transport of vitellogenin in Xenopus oocytes: An autoradiographic study" @default.
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- W2072074580 doi "https://doi.org/10.1016/0012-1606(77)90145-2" @default.
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