FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072084068> ?p ?o ?g. }

• W2072084068 abstract "Recent sepsis guidelines have focused on the early identification and risk stratification of patients on presentation. Obesity is associated with alterations in multiple inflammatory regulators similar to changes seen in sepsis, suggesting a potential interaction between the presence of obesity and the severity of illness in sepsis. We performed a retrospective chart review of patients admitted with a primary billing diagnosis of sepsis at a single United States university hospital from 2007 to 2010. Seven hundred and ninety-two charts were identified meeting inclusion criteria. Obesity was defined as a body mass index (BMI) ≥ 30 kg/m2. The data recorded included age, race, sex, vital signs, laboratory values, length of stay, comorbidities, weight, height, and survival to discharge. A modified APACHE II score was calculated to estimate disease severity. The primary outcome variable was inpatient mortality. Survivors had higher average BMI than nonsurvivors (27.6 vs. 26.3 kg/m2, p = 0.03) in unadjusted analysis. Severity of illness and comorbid conditions including cancer were similar across BMI categories. Increased incidence of diabetes mellitus type 2 was associated with increasing BMI (p < 0.01) and was associated with decreased mortality, with an odds ratio of 0.53 compared with nondiabetic patients. After adjusting for age, gender, race, severity of illness, length of stay, and comorbid conditions, the trend of decreased mortality for increased BMI was no longer statistically significant, however diabetes continued to be strongly protective (odds ratio 0.52, p = 0.03). This retrospective analysis suggests obesity may be protective against mortality in septic inpatients. The protective effect of obesity may be dependent on diabetes, possibly through an unidentified hormonal intermediary. Further prospective studies are necessary to elaborate the specific mechanism of this protective effect." @default.
• W2072084068 created "2016-06-24" @default.
• W2072084068 creator A5040110644 @default.
• W2072084068 creator A5056160653 @default.
• W2072084068 creator A5062302785 @default.
• W2072084068 creator A5062972294 @default.
• W2072084068 creator A5085250371 @default.
• W2072084068 date "2013-08-16" @default.
• W2072084068 modified "2023-10-18" @default.
• W2072084068 title "The impact of obesity on sepsis mortality: a retrospective review" @default.
• W2072084068 cites W1497019223 @default.
• W2072084068 cites W1504385222 @default.
• W2072084068 cites W1705177944 @default.
• W2072084068 cites W172403298 @default.
• W2072084068 cites W1977003718 @default.
• W2072084068 cites W1978758539 @default.
• W2072084068 cites W1981118821 @default.
• W2072084068 cites W1986836799 @default.
• W2072084068 cites W2002397505 @default.
• W2072084068 cites W2003671526 @default.
• W2072084068 cites W2004032781 @default.
• W2072084068 cites W2006153994 @default.
• W2072084068 cites W2006558163 @default.
• W2072084068 cites W2013106106 @default.
• W2072084068 cites W2022263354 @default.
• W2072084068 cites W2024620709 @default.
• W2072084068 cites W2028662660 @default.
• W2072084068 cites W2035564739 @default.
• W2072084068 cites W2037587089 @default.
• W2072084068 cites W2040582647 @default.
• W2072084068 cites W2042653501 @default.
• W2072084068 cites W2046859247 @default.
• W2072084068 cites W2049927822 @default.
• W2072084068 cites W2052897079 @default.
• W2072084068 cites W2054156175 @default.
• W2072084068 cites W2059345875 @default.
• W2072084068 cites W2062568233 @default.
• W2072084068 cites W2072963414 @default.
• W2072084068 cites W2074574470 @default.
• W2072084068 cites W2077200944 @default.
• W2072084068 cites W2085074312 @default.
• W2072084068 cites W2096429786 @default.
• W2072084068 cites W2101590720 @default.
• W2072084068 cites W2111648036 @default.
• W2072084068 cites W2115786206 @default.
• W2072084068 cites W2116262659 @default.
• W2072084068 cites W2137143013 @default.
• W2072084068 cites W2138220577 @default.
• W2072084068 cites W2144642243 @default.
• W2072084068 cites W2156545635 @default.
• W2072084068 cites W2163678936 @default.
• W2072084068 cites W2166558587 @default.
• W2072084068 cites W2334337188 @default.
• W2072084068 doi "https://doi.org/10.1186/1471-2334-13-377" @default.
• W2072084068 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3765286" @default.
• W2072084068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23957291" @default.
• W2072084068 hasPublicationYear "2013" @default.
• W2072084068 type Work @default.
• W2072084068 sameAs 2072084068 @default.
• W2072084068 citedByCount "57" @default.
• W2072084068 countsByYear W20720840682014 @default.
• W2072084068 countsByYear W20720840682015 @default.
• W2072084068 countsByYear W20720840682016 @default.
• W2072084068 countsByYear W20720840682017 @default.
• W2072084068 countsByYear W20720840682018 @default.
• W2072084068 countsByYear W20720840682019 @default.
• W2072084068 countsByYear W20720840682020 @default.
• W2072084068 countsByYear W20720840682021 @default.
• W2072084068 countsByYear W20720840682023 @default.
• W2072084068 crossrefType "journal-article" @default.
• W2072084068 hasAuthorship W2072084068A5040110644 @default.
• W2072084068 hasAuthorship W2072084068A5056160653 @default.
• W2072084068 hasAuthorship W2072084068A5062302785 @default.
• W2072084068 hasAuthorship W2072084068A5062972294 @default.
• W2072084068 hasAuthorship W2072084068A5085250371 @default.
• W2072084068 hasBestOaLocation W20720840681 @default.
• W2072084068 hasConcept C120665830 @default.
• W2072084068 hasConcept C121332964 @default.
• W2072084068 hasConcept C126322002 @default.
• W2072084068 hasConcept C134018914 @default.
• W2072084068 hasConcept C156957248 @default.
• W2072084068 hasConcept C167135981 @default.
• W2072084068 hasConcept C179755657 @default.
• W2072084068 hasConcept C2778384902 @default.
• W2072084068 hasConcept C2779159551 @default.
• W2072084068 hasConcept C2780221984 @default.
• W2072084068 hasConcept C2780586474 @default.
• W2072084068 hasConcept C2781223611 @default.
• W2072084068 hasConcept C511355011 @default.
• W2072084068 hasConcept C555293320 @default.
• W2072084068 hasConcept C61511704 @default.
• W2072084068 hasConcept C71924100 @default.
• W2072084068 hasConceptScore W2072084068C120665830 @default.
• W2072084068 hasConceptScore W2072084068C121332964 @default.
• W2072084068 hasConceptScore W2072084068C126322002 @default.
• W2072084068 hasConceptScore W2072084068C134018914 @default.
• W2072084068 hasConceptScore W2072084068C156957248 @default.
• W2072084068 hasConceptScore W2072084068C167135981 @default.
• W2072084068 hasConceptScore W2072084068C179755657 @default.
• W2072084068 hasConceptScore W2072084068C2778384902 @default.

• next