Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072131784> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2072131784 endingPage "239" @default.
- W2072131784 startingPage "233" @default.
- W2072131784 abstract "Craniospinal irradiation (CSI) is an essential component of the therapy of medulloblastoma. Because medulloblastoma disseminates via the cerebrospinal fluid (CSF), CSI technique involves the irradiation of all CSF-bearing areas which are at risk for tumor seeding. Underdosing with radiation because of inadequacies in CSI technique will produce dose cold spots which have the potential of serving as a nidus for tumor recurrence. A simple mathematic model of subclinical disease in medulloblastoma based on the available data concerning the radiosensitivity of medulloblastoma cell lines as well as the known clinical dose-response relationships support the hypothesis that for most cases of medulloblastoma, the radiotherapist is working in a range of doses arrayed on the steep portion of the tumor control probability curve. Underdosing of CSF-bearing areas because of technical problems at the junction of the cranial and spinal fields of irradiation, placement of shielding blocks in the cribiform plate-subfrontal region, and/or anatomic errors in the design of the caudal end of the CSI fields may lead to significant risks of tumor relapse. One may debate the necessity of a posterior fossa boost encompassing the entire anatomic posterior fossa rather than the primary tumor volume with a margin. This review critically evaluates the potential impact of CSI technique upon the outcome of treatment for medulloblastoma, and suggests future areas of inquiry." @default.
- W2072131784 created "2016-06-24" @default.
- W2072131784 creator A5042596874 @default.
- W2072131784 date "1996-08-01" @default.
- W2072131784 modified "2023-10-13" @default.
- W2072131784 title "Impact of radiation technique upon the outcome of treatment for medulloblastoma" @default.
- W2072131784 cites W1509802320 @default.
- W2072131784 cites W1964202387 @default.
- W2072131784 cites W1972764522 @default.
- W2072131784 cites W1974817010 @default.
- W2072131784 cites W1978161696 @default.
- W2072131784 cites W1980166977 @default.
- W2072131784 cites W1985331426 @default.
- W2072131784 cites W1986557288 @default.
- W2072131784 cites W1989529412 @default.
- W2072131784 cites W1991001694 @default.
- W2072131784 cites W1991896137 @default.
- W2072131784 cites W1997501131 @default.
- W2072131784 cites W1999286897 @default.
- W2072131784 cites W2000344013 @default.
- W2072131784 cites W2006872831 @default.
- W2072131784 cites W2007803784 @default.
- W2072131784 cites W2008214121 @default.
- W2072131784 cites W2009282059 @default.
- W2072131784 cites W2024455788 @default.
- W2072131784 cites W2027294932 @default.
- W2072131784 cites W2032530681 @default.
- W2072131784 cites W2034622647 @default.
- W2072131784 cites W2041759695 @default.
- W2072131784 cites W2043432825 @default.
- W2072131784 cites W2062033425 @default.
- W2072131784 cites W2062451107 @default.
- W2072131784 cites W2069010139 @default.
- W2072131784 cites W2069673587 @default.
- W2072131784 cites W2069744433 @default.
- W2072131784 cites W2075850416 @default.
- W2072131784 cites W2083874203 @default.
- W2072131784 cites W2084242505 @default.
- W2072131784 cites W2104996683 @default.
- W2072131784 cites W2120098513 @default.
- W2072131784 cites W2147423434 @default.
- W2072131784 cites W2156869994 @default.
- W2072131784 cites W2162293287 @default.
- W2072131784 cites W2515539562 @default.
- W2072131784 cites W260831722 @default.
- W2072131784 doi "https://doi.org/10.1016/s0360-3016(96)00276-3" @default.
- W2072131784 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8823280" @default.
- W2072131784 hasPublicationYear "1996" @default.
- W2072131784 type Work @default.
- W2072131784 sameAs 2072131784 @default.
- W2072131784 citedByCount "55" @default.
- W2072131784 countsByYear W20721317842012 @default.
- W2072131784 countsByYear W20721317842013 @default.
- W2072131784 countsByYear W20721317842014 @default.
- W2072131784 countsByYear W20721317842015 @default.
- W2072131784 countsByYear W20721317842016 @default.
- W2072131784 countsByYear W20721317842018 @default.
- W2072131784 countsByYear W20721317842019 @default.
- W2072131784 countsByYear W20721317842020 @default.
- W2072131784 countsByYear W20721317842022 @default.
- W2072131784 countsByYear W20721317842023 @default.
- W2072131784 crossrefType "journal-article" @default.
- W2072131784 hasAuthorship W2072131784A5042596874 @default.
- W2072131784 hasConcept C126838900 @default.
- W2072131784 hasConcept C2780789225 @default.
- W2072131784 hasConcept C2989005 @default.
- W2072131784 hasConcept C2993788527 @default.
- W2072131784 hasConcept C502942594 @default.
- W2072131784 hasConcept C509974204 @default.
- W2072131784 hasConcept C71924100 @default.
- W2072131784 hasConceptScore W2072131784C126838900 @default.
- W2072131784 hasConceptScore W2072131784C2780789225 @default.
- W2072131784 hasConceptScore W2072131784C2989005 @default.
- W2072131784 hasConceptScore W2072131784C2993788527 @default.
- W2072131784 hasConceptScore W2072131784C502942594 @default.
- W2072131784 hasConceptScore W2072131784C509974204 @default.
- W2072131784 hasConceptScore W2072131784C71924100 @default.
- W2072131784 hasIssue "1" @default.
- W2072131784 hasLocation W20721317841 @default.
- W2072131784 hasLocation W20721317842 @default.
- W2072131784 hasOpenAccess W2072131784 @default.
- W2072131784 hasPrimaryLocation W20721317841 @default.
- W2072131784 hasRelatedWork W1974237274 @default.
- W2072131784 hasRelatedWork W1984226852 @default.
- W2072131784 hasRelatedWork W2062443378 @default.
- W2072131784 hasRelatedWork W2166813049 @default.
- W2072131784 hasRelatedWork W2374080520 @default.
- W2072131784 hasRelatedWork W2895538388 @default.
- W2072131784 hasRelatedWork W3094500874 @default.
- W2072131784 hasRelatedWork W4232637926 @default.
- W2072131784 hasRelatedWork W4251383344 @default.
- W2072131784 hasRelatedWork W4303033928 @default.
- W2072131784 hasVolume "36" @default.
- W2072131784 isParatext "false" @default.
- W2072131784 isRetracted "false" @default.
- W2072131784 magId "2072131784" @default.
- W2072131784 workType "article" @default.