Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072148488> ?p ?o ?g. }
- W2072148488 endingPage "1004" @default.
- W2072148488 startingPage "997" @default.
- W2072148488 abstract "To define the pharmacokinetics of florfenicol in synovial fluid (SYNF) and serum from central venous (CV) and digital venous (DV) blood samples following regional IV perfusion (RIVP) of the distal portion of the hind limb in cows.6 healthy adult cows.In each cow, IV catheters were placed in the dorsal common digital vein (DCDV) and the plantar vein of the lateral digit, and an indwelling catheter was placed in the metatarsophalangeal joint of the left hind limb. A pneumatic tourniquet was applied to the midmetatarsal region. Florfenicol (2.2 mg/kg) was administered into the DCDV. Samples of DV blood, SYNF, and CV (jugular) blood were collected after 0.25, 0.50, and 0.75 hours, and the tourniquet was removed; additional samples were collected at intervals for 24 hours after infusion. Florfenicol analysis was performed via high-performance liquid chromatography.In DV blood, CV blood, and SYNF, mean +/- SD maximum florfenicol concentration was 714.79 +/- 301.93 microg/mL, 5.90 +/- 1.37 microg/mL, and 39.19 +/- 29.42 microg/mL, respectively; area under the concentration versus time curve was 488.14 +/- 272.53 h*microg*mL(1), 23.10 +/- 6.91 h*microg*mL(1), and 113.82 +/- 54.71 h*microg*mL(1), respectively; and half-life was 4.09 +/- 1.93 hours, 4.77 +/- 0.67 hours, and 3.81 +/- 0.81 hours, respectively.Following RIVP, high florfenicol concentrations were achieved in DV blood and SYNF, whereas the CV blood concentration remained low. In cattle, RIVP of florfenicol may be useful in the treatment of infectious processes involving the distal portion of limbs." @default.
- W2072148488 created "2016-06-24" @default.
- W2072148488 creator A5006466049 @default.
- W2072148488 creator A5016943199 @default.
- W2072148488 creator A5034204418 @default.
- W2072148488 creator A5050713327 @default.
- W2072148488 creator A5076137251 @default.
- W2072148488 date "2008-08-01" @default.
- W2072148488 modified "2023-10-14" @default.
- W2072148488 title "Pharmacokinetics of florfenicol in serum and synovial fluid after regional intravenous perfusion in the distal portion of the hind limb of adult cows" @default.
- W2072148488 cites W1981680605 @default.
- W2072148488 cites W1988040266 @default.
- W2072148488 cites W1990076650 @default.
- W2072148488 cites W1991802030 @default.
- W2072148488 cites W2005146576 @default.
- W2072148488 cites W2009099871 @default.
- W2072148488 cites W2012454155 @default.
- W2072148488 cites W2012507649 @default.
- W2072148488 cites W2020629747 @default.
- W2072148488 cites W2032557655 @default.
- W2072148488 cites W2035804561 @default.
- W2072148488 cites W2043065765 @default.
- W2072148488 cites W2044289950 @default.
- W2072148488 cites W2052373592 @default.
- W2072148488 cites W2060994499 @default.
- W2072148488 cites W2067196841 @default.
- W2072148488 cites W2075784108 @default.
- W2072148488 cites W2077061859 @default.
- W2072148488 cites W2078275669 @default.
- W2072148488 cites W2100482235 @default.
- W2072148488 cites W2105083638 @default.
- W2072148488 cites W2111804871 @default.
- W2072148488 cites W2113562361 @default.
- W2072148488 cites W2113892225 @default.
- W2072148488 cites W2119224827 @default.
- W2072148488 cites W2120065744 @default.
- W2072148488 cites W2132274499 @default.
- W2072148488 cites W2135021243 @default.
- W2072148488 cites W2135226506 @default.
- W2072148488 cites W2136596005 @default.
- W2072148488 cites W2137324325 @default.
- W2072148488 cites W2141831636 @default.
- W2072148488 cites W2144758432 @default.
- W2072148488 cites W2148893654 @default.
- W2072148488 cites W2149563600 @default.
- W2072148488 cites W2157426231 @default.
- W2072148488 cites W2160589065 @default.
- W2072148488 cites W2165432792 @default.
- W2072148488 cites W2254943433 @default.
- W2072148488 cites W2297215755 @default.
- W2072148488 cites W67331885 @default.
- W2072148488 doi "https://doi.org/10.2460/ajvr.69.8.997" @default.
- W2072148488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18672962" @default.
- W2072148488 hasPublicationYear "2008" @default.
- W2072148488 type Work @default.
- W2072148488 sameAs 2072148488 @default.
- W2072148488 citedByCount "34" @default.
- W2072148488 countsByYear W20721484882012 @default.
- W2072148488 countsByYear W20721484882013 @default.
- W2072148488 countsByYear W20721484882014 @default.
- W2072148488 countsByYear W20721484882015 @default.
- W2072148488 countsByYear W20721484882016 @default.
- W2072148488 countsByYear W20721484882017 @default.
- W2072148488 countsByYear W20721484882018 @default.
- W2072148488 countsByYear W20721484882019 @default.
- W2072148488 countsByYear W20721484882020 @default.
- W2072148488 countsByYear W20721484882021 @default.
- W2072148488 countsByYear W20721484882022 @default.
- W2072148488 countsByYear W20721484882023 @default.
- W2072148488 crossrefType "journal-article" @default.
- W2072148488 hasAuthorship W2072148488A5006466049 @default.
- W2072148488 hasAuthorship W2072148488A5016943199 @default.
- W2072148488 hasAuthorship W2072148488A5034204418 @default.
- W2072148488 hasAuthorship W2072148488A5050713327 @default.
- W2072148488 hasAuthorship W2072148488A5076137251 @default.
- W2072148488 hasBestOaLocation W20721484881 @default.
- W2072148488 hasConcept C112705442 @default.
- W2072148488 hasConcept C126322002 @default.
- W2072148488 hasConcept C141071460 @default.
- W2072148488 hasConcept C146957229 @default.
- W2072148488 hasConcept C185592680 @default.
- W2072148488 hasConcept C2777202286 @default.
- W2072148488 hasConcept C2777956836 @default.
- W2072148488 hasConcept C2779400597 @default.
- W2072148488 hasConcept C2780663544 @default.
- W2072148488 hasConcept C2780690508 @default.
- W2072148488 hasConcept C42219234 @default.
- W2072148488 hasConcept C43044207 @default.
- W2072148488 hasConcept C501593827 @default.
- W2072148488 hasConcept C55493867 @default.
- W2072148488 hasConcept C71924100 @default.
- W2072148488 hasConceptScore W2072148488C112705442 @default.
- W2072148488 hasConceptScore W2072148488C126322002 @default.
- W2072148488 hasConceptScore W2072148488C141071460 @default.
- W2072148488 hasConceptScore W2072148488C146957229 @default.
- W2072148488 hasConceptScore W2072148488C185592680 @default.
- W2072148488 hasConceptScore W2072148488C2777202286 @default.
- W2072148488 hasConceptScore W2072148488C2777956836 @default.