Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072156980> ?p ?o ?g. }
- W2072156980 endingPage "44" @default.
- W2072156980 startingPage "39" @default.
- W2072156980 abstract "CX3CL1 or Fractalkine is a peculiar chemokine that can exist either in a soluble form, like all the other chemokines, and as a cell membrane molecule. CX3CL1 is one of the most expressed chemokines in the central nervous system, where it regulates the communication between neurons, glia and microglia. CX3CR1-expressing microglia may have an important role in limiting tissue injury during inflammation and neuro-degeneration. Recent evidence has implicated CX3CL1 and its cognate receptor CX3CR1 in cancer. Tumors of neural origin (glioma, neuroblastoma) express CX3CR1 which is involved in the adhesion, transendothelial migration and mobilization of tumor cells. In addition, tumors of non-neural origin, like prostate, pancreas and breast carcinoma express high levels of the CX3CR1 receptor. As for other chemokine receptors, CX3CR1 expression is associated with increased migration and site specific dissemination. In pancreatic cancer, receptor expression is involved in the perineural invasion and dissemination of neoplastic cells along intra- and extra-pancreatic nerves. This peculiar route of tumor spread is used also by other carcinomas (e.g. prostate, head and neck) and may represent a target for therapeutic intervention." @default.
- W2072156980 created "2016-06-24" @default.
- W2072156980 creator A5015761646 @default.
- W2072156980 creator A5037434863 @default.
- W2072156980 creator A5062677118 @default.
- W2072156980 creator A5065211137 @default.
- W2072156980 creator A5069074637 @default.
- W2072156980 creator A5078160598 @default.
- W2072156980 date "2010-07-01" @default.
- W2072156980 modified "2023-10-04" @default.
- W2072156980 title "Role of CX3CR1/CX3CL1 axis in primary and secondary involvement of the nervous system by cancer" @default.
- W2072156980 cites W1490833936 @default.
- W2072156980 cites W1532654778 @default.
- W2072156980 cites W1585093254 @default.
- W2072156980 cites W1592707856 @default.
- W2072156980 cites W1652900453 @default.
- W2072156980 cites W1969327218 @default.
- W2072156980 cites W1970145694 @default.
- W2072156980 cites W1970170374 @default.
- W2072156980 cites W1972111650 @default.
- W2072156980 cites W1975662731 @default.
- W2072156980 cites W1983205526 @default.
- W2072156980 cites W1983307037 @default.
- W2072156980 cites W1984075660 @default.
- W2072156980 cites W1984115097 @default.
- W2072156980 cites W1986986419 @default.
- W2072156980 cites W1988502442 @default.
- W2072156980 cites W1999363307 @default.
- W2072156980 cites W1999392449 @default.
- W2072156980 cites W2005804545 @default.
- W2072156980 cites W2006166044 @default.
- W2072156980 cites W2007287932 @default.
- W2072156980 cites W2008286016 @default.
- W2072156980 cites W2010463369 @default.
- W2072156980 cites W2014495235 @default.
- W2072156980 cites W2016861424 @default.
- W2072156980 cites W2019620455 @default.
- W2072156980 cites W2022021401 @default.
- W2072156980 cites W2023624246 @default.
- W2072156980 cites W2026690365 @default.
- W2072156980 cites W2032266995 @default.
- W2072156980 cites W2032618901 @default.
- W2072156980 cites W2034913211 @default.
- W2072156980 cites W2042452988 @default.
- W2072156980 cites W2043676834 @default.
- W2072156980 cites W2044330918 @default.
- W2072156980 cites W2052193782 @default.
- W2072156980 cites W2060425936 @default.
- W2072156980 cites W2061294496 @default.
- W2072156980 cites W2063270450 @default.
- W2072156980 cites W2066810823 @default.
- W2072156980 cites W2067740832 @default.
- W2072156980 cites W2071832924 @default.
- W2072156980 cites W2075006530 @default.
- W2072156980 cites W2076797886 @default.
- W2072156980 cites W2084114471 @default.
- W2072156980 cites W2085364726 @default.
- W2072156980 cites W2091429713 @default.
- W2072156980 cites W2093106975 @default.
- W2072156980 cites W2093387515 @default.
- W2072156980 cites W2096151993 @default.
- W2072156980 cites W2105207870 @default.
- W2072156980 cites W2108404067 @default.
- W2072156980 cites W2113107925 @default.
- W2072156980 cites W2114200189 @default.
- W2072156980 cites W2116018770 @default.
- W2072156980 cites W2119752261 @default.
- W2072156980 cites W2123105952 @default.
- W2072156980 cites W2126972955 @default.
- W2072156980 cites W2131967611 @default.
- W2072156980 cites W2132614080 @default.
- W2072156980 cites W2132852509 @default.
- W2072156980 cites W2133106492 @default.
- W2072156980 cites W2133311030 @default.
- W2072156980 cites W2146061835 @default.
- W2072156980 cites W2147932294 @default.
- W2072156980 cites W2150949781 @default.
- W2072156980 cites W2151119661 @default.
- W2072156980 cites W2152770189 @default.
- W2072156980 cites W2154210454 @default.
- W2072156980 cites W2156323704 @default.
- W2072156980 cites W2163487275 @default.
- W2072156980 cites W2167837285 @default.
- W2072156980 doi "https://doi.org/10.1016/j.jneuroim.2010.05.007" @default.
- W2072156980 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20630606" @default.
- W2072156980 hasPublicationYear "2010" @default.
- W2072156980 type Work @default.
- W2072156980 sameAs 2072156980 @default.
- W2072156980 citedByCount "85" @default.
- W2072156980 countsByYear W20721569802012 @default.
- W2072156980 countsByYear W20721569802013 @default.
- W2072156980 countsByYear W20721569802014 @default.
- W2072156980 countsByYear W20721569802015 @default.
- W2072156980 countsByYear W20721569802016 @default.
- W2072156980 countsByYear W20721569802017 @default.
- W2072156980 countsByYear W20721569802018 @default.
- W2072156980 countsByYear W20721569802019 @default.
- W2072156980 countsByYear W20721569802020 @default.