FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072174397> ?p ?o ?g. }

• W2072174397 endingPage "274" @default.
• W2072174397 startingPage "267" @default.
• W2072174397 abstract "Mucosal-associated invariant T (MAIT) cells contribute to protection against certain microorganism infections. The aims of this study were to examine the levels of MAIT cells in pulmonary tuberculosis (TB) and nontuberculous mycobacteria (NTM) lung disease patients, to evaluate the clinical relevance of MAIT cell levels, and to investigate the functions of MAIT cells. Patients with pulmonary TB (n = 35), NTM (n = 29), and healthy controls (n = 75) were enrolled in the study. MAIT cell levels and functions were measured by flow cytometry. Circluating MAIT cell levels were found to be reduced in TB and NTM patients. MAIT cell deficiency reflects a variety of clinical conditions. In particular, MAIT cell numbers were significantly correlated with sputum AFB positivity, extent of disease, hemoglobin levels, lymphocyte counts, CRP and ESR levels. MAIT cells in TB patients failed to produce interferon-γ irrespective of the mode of stimulation, whereas NTM patients displayed a defect in MR1-dependent signaling pathway. Notably, an elevated expression of programmed death-1 was also associated with MAIT cell deficiency in TB. This study shows that MAIT cells are numerically and functionally deficient in TB and NTM patients and these deficiencies could contribute to immune system dysreguation in mycobacterial infection." @default.
• W2072174397 created "2016-06-24" @default.
• W2072174397 creator A5000342317 @default.
• W2072174397 creator A5006407937 @default.
• W2072174397 creator A5006915740 @default.
• W2072174397 creator A5007675211 @default.
• W2072174397 creator A5016808511 @default.
• W2072174397 creator A5039040546 @default.
• W2072174397 creator A5042658128 @default.
• W2072174397 creator A5043703733 @default.
• W2072174397 creator A5043724477 @default.
• W2072174397 creator A5055314265 @default.
• W2072174397 creator A5067036969 @default.
• W2072174397 creator A5068223655 @default.
• W2072174397 date "2015-05-01" @default.
• W2072174397 modified "2023-10-18" @default.
• W2072174397 title "Mucosal-associated invariant T cells are numerically and functionally deficient in patients with mycobacterial infection and reflect disease activity" @default.
• W2072174397 cites W1930123064 @default.
• W2072174397 cites W1966464958 @default.
• W2072174397 cites W1966621240 @default.
• W2072174397 cites W1977200683 @default.
• W2072174397 cites W1981700081 @default.
• W2072174397 cites W1982688638 @default.
• W2072174397 cites W1986910893 @default.
• W2072174397 cites W1994087084 @default.
• W2072174397 cites W2001908390 @default.
• W2072174397 cites W2004811983 @default.
• W2072174397 cites W2008617601 @default.
• W2072174397 cites W2008734511 @default.
• W2072174397 cites W2018090262 @default.
• W2072174397 cites W2027160668 @default.
• W2072174397 cites W2029115223 @default.
• W2072174397 cites W2030817385 @default.
• W2072174397 cites W2031457861 @default.
• W2072174397 cites W2049739427 @default.
• W2072174397 cites W2065252029 @default.
• W2072174397 cites W2066950435 @default.
• W2072174397 cites W2067824142 @default.
• W2072174397 cites W2073247934 @default.
• W2072174397 cites W2079641738 @default.
• W2072174397 cites W2091465381 @default.
• W2072174397 cites W2098451762 @default.
• W2072174397 cites W2099092516 @default.
• W2072174397 cites W2108911207 @default.
• W2072174397 cites W2109544983 @default.
• W2072174397 cites W2117410945 @default.
• W2072174397 cites W2119896120 @default.
• W2072174397 cites W2129681697 @default.
• W2072174397 cites W2141895032 @default.
• W2072174397 cites W2142447693 @default.
• W2072174397 cites W2143709477 @default.
• W2072174397 cites W2155464214 @default.
• W2072174397 cites W2161930955 @default.
• W2072174397 cites W4211162439 @default.
• W2072174397 doi "https://doi.org/10.1016/j.tube.2015.03.004" @default.
• W2072174397 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25837440" @default.
• W2072174397 hasPublicationYear "2015" @default.
• W2072174397 type Work @default.
• W2072174397 sameAs 2072174397 @default.
• W2072174397 citedByCount "85" @default.
• W2072174397 countsByYear W20721743972015 @default.
• W2072174397 countsByYear W20721743972016 @default.
• W2072174397 countsByYear W20721743972017 @default.
• W2072174397 countsByYear W20721743972018 @default.
• W2072174397 countsByYear W20721743972019 @default.
• W2072174397 countsByYear W20721743972020 @default.
• W2072174397 countsByYear W20721743972021 @default.
• W2072174397 countsByYear W20721743972022 @default.
• W2072174397 countsByYear W20721743972023 @default.
• W2072174397 crossrefType "journal-article" @default.
• W2072174397 hasAuthorship W2072174397A5000342317 @default.
• W2072174397 hasAuthorship W2072174397A5006407937 @default.
• W2072174397 hasAuthorship W2072174397A5006915740 @default.
• W2072174397 hasAuthorship W2072174397A5007675211 @default.
• W2072174397 hasAuthorship W2072174397A5016808511 @default.
• W2072174397 hasAuthorship W2072174397A5039040546 @default.
• W2072174397 hasAuthorship W2072174397A5042658128 @default.
• W2072174397 hasAuthorship W2072174397A5043703733 @default.
• W2072174397 hasAuthorship W2072174397A5043724477 @default.
• W2072174397 hasAuthorship W2072174397A5055314265 @default.
• W2072174397 hasAuthorship W2072174397A5067036969 @default.
• W2072174397 hasAuthorship W2072174397A5068223655 @default.
• W2072174397 hasConcept C126322002 @default.
• W2072174397 hasConcept C142724271 @default.
• W2072174397 hasConcept C203014093 @default.
• W2072174397 hasConcept C2776301714 @default.
• W2072174397 hasConcept C2778679867 @default.
• W2072174397 hasConcept C2779134260 @default.
• W2072174397 hasConcept C2780374374 @default.
• W2072174397 hasConcept C2781069245 @default.
• W2072174397 hasConcept C553184892 @default.
• W2072174397 hasConcept C71924100 @default.
• W2072174397 hasConcept C86803240 @default.
• W2072174397 hasConcept C8891405 @default.
• W2072174397 hasConceptScore W2072174397C126322002 @default.
• W2072174397 hasConceptScore W2072174397C142724271 @default.
• W2072174397 hasConceptScore W2072174397C203014093 @default.
• W2072174397 hasConceptScore W2072174397C2776301714 @default.

• next