FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072206673> ?p ?o ?g. }

• W2072206673 endingPage "151" @default.
• W2072206673 startingPage "144" @default.
• W2072206673 abstract "Herpes simplex virus (HSV) has been shown to cause central nervous system demyelination in experimental animals and several studies have implicated HSV in the aetiology of multiple sclerosis (MS). We have used the polymerase chain reaction to look for DNA of both type 1 HSV (HSV-1) and type 2 HSV (HSV-2) in formalin-fixed paraffin-embedded brain tissues from patients with MS and other neurological diseases. Primers which amplify a fragment of the normal cellular gene c-myc were included in the reactions to assess the preservation of DNA in the tissue samples. 77 plaques of demyelination from 23 patients with MS were examined. HSV-1 DNA was amplified from only one plaque. This plaque involved the trigeminal root entry zone in the pons and it is suggested that the presence of viral DNA was related to the site examined rather than to the demyelination per se. HSV-2 DNA was amplified from none of the plaques. As expected, HSV-1 DNA was detected in the brains of 6 patients who died of HSV-1 encephalitis and HSV-2 DNA was amplified from the brain of a neonate with congenital HSV-2 infection. In sections of brain from 39 patients with a wide range of other neurological diseases HSV-1 DNA was detected in the pons of only 1 patient, who had AIDS associated with cytomegalovirus ventriculitis; subsequent investigation confirmed the presence of concomitant HSV-1 brain stem infection.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2072206673 created "2016-06-24" @default.
• W2072206673 creator A5016566297 @default.
• W2072206673 creator A5053163430 @default.
• W2072206673 creator A5076034120 @default.
• W2072206673 date "1992-12-01" @default.
• W2072206673 modified "2023-09-26" @default.
• W2072206673 title "PCR-mediated search for herpes simplex virus DNA in sections of brain from patients with multiple sclerosis and other neurological disorders" @default.
• W2072206673 cites W1250594259 @default.
• W2072206673 cites W1979485830 @default.
• W2072206673 cites W1990573833 @default.
• W2072206673 cites W2000388934 @default.
• W2072206673 cites W2010441865 @default.
• W2072206673 cites W2013132534 @default.
• W2072206673 cites W2017245132 @default.
• W2072206673 cites W2033607757 @default.
• W2072206673 cites W2042941945 @default.
• W2072206673 cites W2044952849 @default.
• W2072206673 cites W2046422199 @default.
• W2072206673 cites W2046492131 @default.
• W2072206673 cites W2047480444 @default.
• W2072206673 cites W2054066061 @default.
• W2072206673 cites W2055649014 @default.
• W2072206673 cites W2060249953 @default.
• W2072206673 cites W2063739175 @default.
• W2072206673 cites W2064258585 @default.
• W2072206673 cites W2070284024 @default.
• W2072206673 cites W2071622633 @default.
• W2072206673 cites W2074744403 @default.
• W2072206673 cites W2074961185 @default.
• W2072206673 cites W2079326686 @default.
• W2072206673 cites W2089001114 @default.
• W2072206673 cites W2093294491 @default.
• W2072206673 cites W2110610601 @default.
• W2072206673 cites W2111853038 @default.
• W2072206673 cites W2136798456 @default.
• W2072206673 cites W2137977906 @default.
• W2072206673 cites W2140630337 @default.
• W2072206673 cites W2147283387 @default.
• W2072206673 cites W2313130310 @default.
• W2072206673 cites W2321442574 @default.
• W2072206673 doi "https://doi.org/10.1016/0022-510x(92)90242-d" @default.
• W2072206673 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1336795" @default.
• W2072206673 hasPublicationYear "1992" @default.
• W2072206673 type Work @default.
• W2072206673 sameAs 2072206673 @default.
• W2072206673 citedByCount "28" @default.
• W2072206673 countsByYear W20722066732020 @default.
• W2072206673 countsByYear W20722066732021 @default.
• W2072206673 countsByYear W20722066732022 @default.
• W2072206673 countsByYear W20722066732023 @default.
• W2072206673 crossrefType "journal-article" @default.
• W2072206673 hasAuthorship W2072206673A5016566297 @default.
• W2072206673 hasAuthorship W2072206673A5053163430 @default.
• W2072206673 hasAuthorship W2072206673A5076034120 @default.
• W2072206673 hasConcept C104317684 @default.
• W2072206673 hasConcept C126322002 @default.
• W2072206673 hasConcept C142724271 @default.
• W2072206673 hasConcept C159047783 @default.
• W2072206673 hasConcept C203014093 @default.
• W2072206673 hasConcept C2522874641 @default.
• W2072206673 hasConcept C2776409557 @default.
• W2072206673 hasConcept C2778897929 @default.
• W2072206673 hasConcept C2780640218 @default.
• W2072206673 hasConcept C2780727368 @default.
• W2072206673 hasConcept C2781196997 @default.
• W2072206673 hasConcept C36372059 @default.
• W2072206673 hasConcept C49105822 @default.
• W2072206673 hasConcept C54355233 @default.
• W2072206673 hasConcept C552990157 @default.
• W2072206673 hasConcept C55493867 @default.
• W2072206673 hasConcept C71924100 @default.
• W2072206673 hasConcept C83455156 @default.
• W2072206673 hasConcept C86803240 @default.
• W2072206673 hasConceptScore W2072206673C104317684 @default.
• W2072206673 hasConceptScore W2072206673C126322002 @default.
• W2072206673 hasConceptScore W2072206673C142724271 @default.
• W2072206673 hasConceptScore W2072206673C159047783 @default.
• W2072206673 hasConceptScore W2072206673C203014093 @default.
• W2072206673 hasConceptScore W2072206673C2522874641 @default.
• W2072206673 hasConceptScore W2072206673C2776409557 @default.
• W2072206673 hasConceptScore W2072206673C2778897929 @default.
• W2072206673 hasConceptScore W2072206673C2780640218 @default.
• W2072206673 hasConceptScore W2072206673C2780727368 @default.
• W2072206673 hasConceptScore W2072206673C2781196997 @default.
• W2072206673 hasConceptScore W2072206673C36372059 @default.
• W2072206673 hasConceptScore W2072206673C49105822 @default.
• W2072206673 hasConceptScore W2072206673C54355233 @default.
• W2072206673 hasConceptScore W2072206673C552990157 @default.
• W2072206673 hasConceptScore W2072206673C55493867 @default.
• W2072206673 hasConceptScore W2072206673C71924100 @default.
• W2072206673 hasConceptScore W2072206673C83455156 @default.
• W2072206673 hasConceptScore W2072206673C86803240 @default.
• W2072206673 hasIssue "2" @default.
• W2072206673 hasLocation W20722066731 @default.
• W2072206673 hasLocation W20722066732 @default.
• W2072206673 hasOpenAccess W2072206673 @default.
• W2072206673 hasPrimaryLocation W20722066731 @default.

• next