FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072218967> ?p ?o ?g. }

• W2072218967 abstract "The demonstration of fine control over nanomaterials within biological systems, particularly in live cells, is integral for the successful implementation of nanoparticles (NPs) in biomedical applications. Here, we show the ability to differentially label the endocytic pathway of mammalian cells in a spatiotemporal manner utilizing fluorescent nanocolloids (NCs) doped with a perylene-based dye. EDC-based conjugation of green- and red-emitting NCs to the iron transport protein transferrin resulted in stable bioconjugates that were efficiently endocytosed by HEK 293T/17 cells. The staggered delivery of the bioconjugates allowed for the time-resolved, differential labeling of distinct vesicular compartments along the endocytic pathway in a nontoxic manner. We further demonstrated the ability of the NCs to be impregnated with the anticancer therapeutic, doxorubicin. Delivery of the drug-doped nanoconjugates resulted in the intracellular release and nuclear accumulation of doxorubicin in a time- and dose-dependent manner. We discuss our results in the context of the utility of such materials for NP-mediated drug delivery applications." @default.
• W2072218967 created "2016-06-24" @default.
• W2072218967 creator A5012704895 @default.
• W2072218967 creator A5016009548 @default.
• W2072218967 creator A5018163302 @default.
• W2072218967 creator A5020016493 @default.
• W2072218967 creator A5042140497 @default.
• W2072218967 creator A5075761835 @default.
• W2072218967 date "2013-02-22" @default.
• W2072218967 modified "2023-09-23" @default.
• W2072218967 title "Fluorescent nanocolloids for differential labeling of the endocytic pathway and drug delivery applications" @default.
• W2072218967 cites W1987924718 @default.
• W2072218967 cites W1992542552 @default.
• W2072218967 cites W1994454165 @default.
• W2072218967 cites W2011032800 @default.
• W2072218967 cites W2044202701 @default.
• W2072218967 cites W2044716277 @default.
• W2072218967 cites W2055051767 @default.
• W2072218967 cites W2057460212 @default.
• W2072218967 cites W2067944387 @default.
• W2072218967 cites W2089657872 @default.
• W2072218967 cites W2120062392 @default.
• W2072218967 cites W2128958387 @default.
• W2072218967 cites W2766250687 @default.
• W2072218967 doi "https://doi.org/10.1117/12.2007749" @default.
• W2072218967 hasPublicationYear "2013" @default.
• W2072218967 type Work @default.
• W2072218967 sameAs 2072218967 @default.
• W2072218967 citedByCount "0" @default.
• W2072218967 crossrefType "proceedings-article" @default.
• W2072218967 hasAuthorship W2072218967A5012704895 @default.
• W2072218967 hasAuthorship W2072218967A5016009548 @default.
• W2072218967 hasAuthorship W2072218967A5018163302 @default.
• W2072218967 hasAuthorship W2072218967A5020016493 @default.
• W2072218967 hasAuthorship W2072218967A5042140497 @default.
• W2072218967 hasAuthorship W2072218967A5075761835 @default.
• W2072218967 hasConcept C104317684 @default.
• W2072218967 hasConcept C121332964 @default.
• W2072218967 hasConcept C12554922 @default.
• W2072218967 hasConcept C1491633281 @default.
• W2072218967 hasConcept C151730666 @default.
• W2072218967 hasConcept C171250308 @default.
• W2072218967 hasConcept C174510640 @default.
• W2072218967 hasConcept C185592680 @default.
• W2072218967 hasConcept C192562407 @default.
• W2072218967 hasConcept C2776694085 @default.
• W2072218967 hasConcept C2779343474 @default.
• W2072218967 hasConcept C2779820397 @default.
• W2072218967 hasConcept C2781303535 @default.
• W2072218967 hasConcept C28005876 @default.
• W2072218967 hasConcept C54355233 @default.
• W2072218967 hasConcept C55493867 @default.
• W2072218967 hasConcept C62520636 @default.
• W2072218967 hasConcept C79747257 @default.
• W2072218967 hasConcept C79879829 @default.
• W2072218967 hasConcept C86803240 @default.
• W2072218967 hasConcept C91881484 @default.
• W2072218967 hasConcept C95444343 @default.
• W2072218967 hasConceptScore W2072218967C104317684 @default.
• W2072218967 hasConceptScore W2072218967C121332964 @default.
• W2072218967 hasConceptScore W2072218967C12554922 @default.
• W2072218967 hasConceptScore W2072218967C1491633281 @default.
• W2072218967 hasConceptScore W2072218967C151730666 @default.
• W2072218967 hasConceptScore W2072218967C171250308 @default.
• W2072218967 hasConceptScore W2072218967C174510640 @default.
• W2072218967 hasConceptScore W2072218967C185592680 @default.
• W2072218967 hasConceptScore W2072218967C192562407 @default.
• W2072218967 hasConceptScore W2072218967C2776694085 @default.
• W2072218967 hasConceptScore W2072218967C2779343474 @default.
• W2072218967 hasConceptScore W2072218967C2779820397 @default.
• W2072218967 hasConceptScore W2072218967C2781303535 @default.
• W2072218967 hasConceptScore W2072218967C28005876 @default.
• W2072218967 hasConceptScore W2072218967C54355233 @default.
• W2072218967 hasConceptScore W2072218967C55493867 @default.
• W2072218967 hasConceptScore W2072218967C62520636 @default.
• W2072218967 hasConceptScore W2072218967C79747257 @default.
• W2072218967 hasConceptScore W2072218967C79879829 @default.
• W2072218967 hasConceptScore W2072218967C86803240 @default.
• W2072218967 hasConceptScore W2072218967C91881484 @default.
• W2072218967 hasConceptScore W2072218967C95444343 @default.
• W2072218967 hasLocation W20722189671 @default.
• W2072218967 hasOpenAccess W2072218967 @default.
• W2072218967 hasPrimaryLocation W20722189671 @default.
• W2072218967 hasRelatedWork W1909116856 @default.
• W2072218967 hasRelatedWork W1995555037 @default.
• W2072218967 hasRelatedWork W2007123529 @default.
• W2072218967 hasRelatedWork W2021929306 @default.
• W2072218967 hasRelatedWork W2045239572 @default.
• W2072218967 hasRelatedWork W2050851212 @default.
• W2072218967 hasRelatedWork W2069084989 @default.
• W2072218967 hasRelatedWork W2087836557 @default.
• W2072218967 hasRelatedWork W2168044659 @default.
• W2072218967 hasRelatedWork W2168733800 @default.
• W2072218967 hasRelatedWork W2317606986 @default.
• W2072218967 hasRelatedWork W2317987908 @default.
• W2072218967 hasRelatedWork W2564677988 @default.
• W2072218967 hasRelatedWork W2618099088 @default.
• W2072218967 hasRelatedWork W2752570599 @default.
• W2072218967 hasRelatedWork W2772793944 @default.
• W2072218967 hasRelatedWork W2793682815 @default.

• next